ReviewCardiology research2022
Quadricuspid Aortic Valve: An Introduction for Clinicians.
Review in Cardiology research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.
- Transcatheter aortic valve replacement in quadricuspid aortic valve: a systematic review and meta-analysis.Frontiers in cardiovascular medicine · 2025Pooled it
- Rare case of quadricuspid aortic valve: A case report.Radiology case reports · 2026Article
- First LDLRAP1 and Recurrent LDLR Mutations in Tunisian Families With Familial Hypercholesterolemia.Journal of cellular and molecular medicine · 2026Article
- A rare HCN4 variant combined with sick sinus syndrome, left ventricular noncompaction, and complex congenital heart disease.Channels (Austin, Tex.) · 2025Article
- Type F Quadricuspid Aortic Valve at Three-Dimensional Transoesophageal Echocardiography.Diagnostics (Basel, Switzerland) · 2025Article
- Severe Aortic Regurgitation Due to Quadricuspid Aortic Valve.JACC. Case reports · 2025Article
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- Thinking Outside the Box: Case Report of a Rare Quadricuspid Aortic Valve as an Underrecognized Cause of Heart Failure and Atrial Fibrillation.Journal of medical cases · 2025Article
- Quadricuspid Aortic Valve: Out of the Shadows, into the Light.Diagnostics (Basel, Switzerland) · 2025Article
- Clinical Variability in Presentation and Management of Quadricuspid Aortic Valve: A Case Series.CASE (Philadelphia, Pa.) · 2025Article
- Age Differences in Aortic Stenosis.Reviews in cardiovascular medicine · 2025Review
- Quadricuspid aortic valve in an asymptomatic young adult: a case report.Annals of medicine and surgery (2012) · 2025Article
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- Transcatheter aortic valve replacement for severe aortic regurgitation in quadricuspid aortic valve: a case report.Frontiers in cardiovascular medicine · 2025Article
- The Diagnosis of Quadricuspid Aortic Valve-Induced Cardiomyopathy: Return to the Basics When in Doubt.Cureus · 2025Article
- Quadricuspid aortic valve with complete heart block: a double whammy.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2024Article
- Asymptomatic, Incidental Quadricuspid Aortic Valve: A Case Report and Discussion of Management.Cureus · 2024Article
- Quadricuspid Aortic Valve: Imaging, Diagnosis, and Prognosis.Texas Heart Institute journal · 2024Article
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Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Quadricuspid aortic valve (QAV) is a congenital heart anomaly in which the aortic valve has four cusps of various size possibilities, as opposed to the three symmetrical cusps generally observed. This cardiac valvular abnormality is rarely identified, with an estimated incidence rate of 0.013% to 0.043%, although recent technological advancements in diagnostics have contributed to an increase in detection. Historically, it had been typically encountered during open heart surgery or postmortem; however, it is presently diagnosed primarily via ultrasound echocardiography, and could go undetected unless specifically considered. It was first reported by Babington in 1847, and since then approximately 300 cases have been published. This condition is sporadically associated with additional congenital cardiovascular defects, with coronary artery irregularities being the most common. In more than half of published QAV incidences it has led to the progressive development of aortic regurgitation (AR) usually
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.