Evidence map›Paper›PMID 35211116›Full record

ArticleFrontiers in immunology2022

Cadherin-11 Regulates Macrophage Development and Function.

Sarah To, Thandiwe Chavula, Mesias Pedroza, Jennifer Smith, Sandeep K Agarwal

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Monocyte-mediated mechanisms in idiopathic pulmonary fibrosis: opportunities for early intervention.Apoptosis : an international journal on programmed cell death · 2026
    Review
  5. Article
  6. Article
  7. Review
  8. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Sarah ToDepartment of Medicine, Section of Immunology, Allergy and Rheumatology, Baylor College of Medicine, Houston, TX, United States.
Thandiwe ChavulaDepartment of Medicine, Section of Immunology, Allergy and Rheumatology, Baylor College of Medicine, Houston, TX, United States.
Mesias PedrozaDepartment of Medicine, Section of Immunology, Allergy and Rheumatology, Baylor College of Medicine, Houston, TX, United States.
Jennifer SmithDepartment of Medicine, Section of Immunology, Allergy and Rheumatology, Baylor College of Medicine, Houston, TX, United States.
Sandeep K AgarwalDepartment of Medicine, Section of Immunology, Allergy and Rheumatology, Baylor College of Medicine, Houston, TX, United States.
Baylor College of Medicine · US

Funding

Tumor BiologyP30CA125123 · NCI · BAYLOR COLLEGE OF MEDICINE · PI DAVID R ROWLEY · 2007 to 2026
$73.9M
Cadherin-11 Regulation Of Dermal Fribrosis And Macrophage FunctionR01AR062056 · NIAMS · BAYLOR COLLEGE OF MEDICINE · PI AGARWAL, SANDEEP K · 2012 to 2016
$1.7M
BD Biosciences Special Order LSRIIS10RR024574 · NCRR · BAYLOR COLLEGE OF MEDICINE · PI LUMPKIN, ELLEN A · 2009 to 2009
$430k
NCI NIH HHS P30 CA125123NCRR NIH HHS S10 RR024574NIAMS NIH HHS R01 AR062056
6 · The paper itself

Abstract

Cadherin-11 (CDH11) is a cell-cell adhesion protein that has previously been reported to play an important role in the pathogenesis of pulmonary fibrosis. It is expressed on macrophages in the fibrotic lung. However, the role of CDH11 on macrophage biology has not yet been studied. We show using immunophenotypic analyses that

Indexed as

AnimalsAntigens, LyBleomycinCadherinsCell AdhesionCell DifferentiationDisease Models, AnimalMacrophagesMaleMiceMonocytesMyeloid Progenitor CellsPulmonary FibrosisAntigens, LyBleomycinCadherinsLy-6C antigen, mouseosteoblast cadherinCadherin-11macrophagesmonocytesphagocytosispolarizationpulmonary fibrosis

Identifiers

PMID35211116
PMCPMC8860974
OpenAlexW4210925162

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.