Evidence map›Paper›PMID 35210966›Full record

ArticleJournal of the Medical Library Association : JMLA2022

Evaluation of adverse drug reaction formatting in drug information mobile phone applications.

Sean M McConachie, Dena Berri, Jewel Konja, Christopher A Giuliano

Abstract read
In one paragraph

Article in Journal of the Medical Library Association : JMLA, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Sean M McConachieet6398@wayne.edu, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University and Beaumont Hospital, Dearborn, Detroit, MI.
Dena Berridena.berri@wayne.edu, PharmD Candidate, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, Detroit, MI.
Jewel Konjaiewel.konia@wayne.edu, PharmD Candidate, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, Detroit, MI.
Christopher A Giulianoek2397@wayne.edu, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University and Ascension St. John Hospital, Detroit, MI.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the differences in presentation (formatting) of adverse drug reaction (ADR) information within drug monographs in commonly used drug information (DI) mobile device applications.

methodsA cross-sectional analysis of ADR formatting of twenty commonly prescribed oral medications within seven DI mobile applications was performed. Databases were assessed for ADR information, including presence of placebo comparisons, severity of ADR, onset of ADR, formatting of ADRs in percentile (quantitative) format or qualitative format, whether references were used to cite information, and whether ADRs are grouped by organ system. Data was collected by two study investigators and discrepancies were resolved via consensus.

resultsThe seven DI mobile applications varied significantly on every analyzed ADR variable with the exception of ADR onset, which was absent in all databases. Significant differences were found for variables known to impact clinical judgment such as placebo comparisons and qualitative versus quantitative formatting. Placebo comparisons were most common among monographs in Lexicomp (30%) but were absent among monographs within other applications. Quantitative information was commonly used in most databases but was absent in Epocrates. Qualitative formatting was present in all Epocrates and Micromedex applications but absent in the majority of other applications. Substantial variations were also found in severity and grouping information.

conclusionSubstantial variation in ADR formatting exists among the most common DI mobile applications. These differences may translate into alternative interpretations of medical information and thus impact clinical judgment. Health care librarians and clinicians should consider ADR formatting when choosing between DI applications.

Indexed as

Cell PhoneDrug-Related Side Effects and Adverse ReactionsMobile ApplicationsPharmaceutical PreparationsCross-Sectional StudiesHumansPharmaceutical Preparationsadverse drug reactionclinical pharmacy information systemsdrug information service

Identifiers

PMID35210966
PMCPMC8830402

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.