Evidence map›Paper›PMID 35210934›Full record

ArticleTransplant international : official journal of the European Society for Organ Transplantation

Kidney Transplants From Donors on Extracorporeal Membrane Oxygenation Prior to Death Are Associated With Better Long-Term Renal Function Compared to Donors After Circulatory Death.

Marilena Gregorini, Elena Ticozzelli, Massimo Abelli, Maria A Grignano, Eleonora F Pattonieri, Alessandro Giacomoni, Luciano De Carlis, Antonio Dell'Acqua, Rossana Caldara, Carlo Socci and 8 more

Open access · goldAbstract read
In one paragraph

Article in Transplant international : official journal of the European Society for Organ Transplantation. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Organ donation from extracorporeal membrane oxygenation and ventricular assist devices in Victoria, Australia: Characteristics and trends.Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine · 2025
    Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 6 institutions in 1 country.

Marilena GregoriniDipartimento di Medicina Interna e Terapia Medica, Università Degli Studi di Pavia, Pavia, Italy.
Elena TicozzelliUnit of General Surgery 2, Department of Surgical Sciences, San Matteo Hospital Foundation (IRCCS), Pavia, Italy.
Massimo AbelliTransplant Unit, IRCCS Fondazione Policlinico San Matteo, Pavia, Italy.
Maria A GrignanoUnit of Nephrology, Dialysis and Transplant, San Matteo Hospital Foundation (IRCCS), Pavia, Italy.
Eleonora F PattonieriUnit of Nephrology, Dialysis and Transplant, San Matteo Hospital Foundation (IRCCS), Pavia, Italy.
Alessandro GiacomoniTransplant Center, Department of General Surgery and Abdominal Transplantation, Niguarda Cà Granda Hospital, Milan, Italy.
Luciano De CarlisDepartment of Medicine and Surgery, University of Milano Bicocca, Milan, Italy.
Antonio Dell'AcquaDepartment of Anesthesia and Critical Care, San Raffaele Scientific Institute (IRCCS), Milan, Italy.
Rossana CaldaraTransplant Unit, Department of General Medicine, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy.
Carlo SocciDepartment of Surgery, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy.
Andrea BottazziICU1 Department of Intensive Medicine, Foundation IRCCS Policlinico San Matteo, Pavia, Italy.
Carmelo LibettaDipartimento di Medicina Interna e Terapia Medica, Università Degli Studi di Pavia, Pavia, Italy.
Vincenzo SepeUnit of Nephrology, Dialysis and Transplant, San Matteo Hospital Foundation (IRCCS), Pavia, Italy.
Stefano MalabarbaUnit of General Surgery 2, Department of Surgical Sciences, San Matteo Hospital Foundation (IRCCS), Pavia, Italy.
Federica ManzoniHealth Promotion, Environmental Epidemiology Unit, Hygiene and Health Prevention Department, Health Protection Agency, Pavia, Italy.
Catherine KlersyBiometry and Clinical Epidemiology Service, Foundation IRCCS Policlinico San Matteo, Pavia, Italy.
Giuseppe PiccoloRegional Transplant Coordination, Milan, Italy.
Teresa RampinoUnit of Nephrology, Dialysis and Transplant, San Matteo Hospital Foundation (IRCCS), Pavia, Italy.
Vita-Salute San Raffaele University · ITAcademy of Emergency Medicine and Care · ITMedica (Italy) · ITPoliclinico San Matteo Fondazione · ITUniversity of Milano-Bicocca · ITUniversity of Pavia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Donation after circulatory death (DCD) allows expansion of the donor pool. We report on 11 years of Italian experience by comparing the outcome of grafts from DCD and extracorporeal membrane oxygenation (ECMO) prior to death donation (EPD), a new donor category. We studied 58 kidney recipients from DCD or EPD and collected donor/recipient clinical characteristics. Primary non function (PNF) and delayed graft function (DGF) rates, dialysis need, hospitalization duration, and patient and graft survival rates were compared. The estimated glomerular filtration rate (eGFR) was measured throughout the follow-up. Better clinical outcomes were achieved with EPD than with DCD despite similar graft and patient survival rates The total warm ischemia time (WIT) was longer in the DCD group than in the EPD group. Pure WIT was the highest in the class II group. The DGF rate was higher in the DCD group than in the EPD group. PNF rate was similar in the groups. Dialysis need was the greatest and hospitalization the longest in the class II DCD group. eGFR was lower in the class II DCD group than in the EPD group. Our results indicate good clinical outcomes of kidney transplants from DCD despite the long "no-touch period" and show that ECMO in the procurement phase improves graft outcome, suggesting EPD as a source for pool expansion.

Indexed as

Extracorporeal Membrane OxygenationKidney TransplantationTissue and Organ ProcurementBrain DeathDelayed Graft FunctionGraft SurvivalHumansKidneyRetrospective StudiesTissue Donorsdonation after circulatory deatheGFRextracorporeal membrane oxygenationhypothermic perfusionrenal transplantation

Identifiers

PMID35210934
PMCPMC8862176
OpenAlexW4210877001

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.