Evidence map›Paper›PMID 35210815›Full record

ArticleJournal of inflammation research2022

HDL-Associated Lipoproteins: Potential Prognostic Biomarkers for Gram-Negative Sepsis.

Guoying Zou, Qing Zhu, Biqiong Ren, Qi Guo, Yuanyuan Wu, Junyu He, Ying Wu, Zhihong Luo

Open access · goldAbstract read
In one paragraph

Article in Journal of inflammation research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 63% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Guoying ZouDepartment of Clinical Laboratory, The Second People's Hospital of Hunan Province, Changsha, Hunan, 410007, People's Republic of China.ORCID 0000-0003-0719-9975
Qing ZhuDepartment of Clinical Laboratory, The Second People's Hospital of Hunan Province, Changsha, Hunan, 410007, People's Republic of China.
Biqiong RenDepartment of Clinical Laboratory, The Second People's Hospital of Hunan Province, Changsha, Hunan, 410007, People's Republic of China.
Qi GuoDepartment of Clinical Laboratory, The Second People's Hospital of Hunan Province, Changsha, Hunan, 410007, People's Republic of China.
Yuanyuan WuDepartment of Clinical Laboratory, The Second People's Hospital of Hunan Province, Changsha, Hunan, 410007, People's Republic of China.
Junyu HeDepartment of Clinical Laboratory, The Second People's Hospital of Hunan Province, Changsha, Hunan, 410007, People's Republic of China.
Ying WuDepartment of Clinical Laboratory, The Second People's Hospital of Hunan Province, Changsha, Hunan, 410007, People's Republic of China.
Zhihong LuoOffice of the Party Committee, The Second People's Hospital of Hunan Province, Changsha, Hunan, 410007, People's Republic of China.
Second People Hospital of Hunan · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo determine the levels of serum HDL-associated apolipoproteins (apoM and apoC) and HDL-binding receptor (scavenger receptor BI, SR-BI) in patients with gram-negative bacteria sepsis (G-sepsis) and to evaluate the value of lipoproteins in the diagnosis, severity and prognosis of G-sepsis. PATIENTS AND

methodsA total of 128 patients with sepsis, 40 patients with system inflammatory reaction syndrome (SIRS) and 40 healthy subjects were enrolled in the Second People's Hospital of Hunan Province from September 2019 to September 2020. The levels and the correlation of lipoproteins were detected and dynamically monitored by enzyme-linked adsorption method, ROC curve for the diagnostic, severity and prognostic value of lipoproteins in G-sepsis.

resultsThe levels of serum HDL-associated lipoproteins in patients with G-sepsis were significantly decreased (

conclusionHDL-associated lipoproteins were correlated with bacterial-infected types, and serum levels of HDL-associated lipoproteins can be used as potential biomarkers for early diagnosis and progress of G-sepsis. ApoM combined with SR-BI could improve the sensitivity and specificity of prognosis assessment.

Indexed as

apolipoproteinbiomarkergram-negative sepsishigh-density lipoproteinprognosis

Identifiers

PMID35210815
PMCPMC8860992
OpenAlexW4212950649

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.