Evidence map›Paper›PMID 35210773›Full record

ArticleNeuropsychiatric disease and treatment2022

Childhood Victimization and Neuroticism Mediate the Effects of Childhood Abuse on Adulthood Depressive Symptoms in Volunteers.

Jiro Masuya, Masahiko Ichiki, Chihiro Morishita, Motoki Higashiyama, Miki Ono, Mina Honyashiki, Yoshio Iwata, Hajime Tanabe, Takeshi Inoue

Open access · goldAbstract read
In one paragraph

Article in Neuropsychiatric disease and treatment, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.5field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Jiro Masuya *Department of Psychiatry, Tokyo Medical University, Shinjuku-ku, Tokyo, 160-0023, Japan.
Masahiko Ichiki *Department of Psychiatry, Tokyo Medical University, Shinjuku-ku, Tokyo, 160-0023, Japan.
Chihiro MorishitaDepartment of Psychiatry, Tokyo Medical University, Shinjuku-ku, Tokyo, 160-0023, Japan.ORCID 0000-0002-8480-9303
Motoki HigashiyamaDepartment of Psychiatry, Tokyo Medical University, Shinjuku-ku, Tokyo, 160-0023, Japan.
Miki OnoDepartment of Psychiatry, Tokyo Medical University, Shinjuku-ku, Tokyo, 160-0023, Japan.
Mina HonyashikiDepartment of Psychiatry, Tokyo Medical University, Shinjuku-ku, Tokyo, 160-0023, Japan.
Yoshio IwataDepartment of Psychiatry, Tokyo Medical University, Shinjuku-ku, Tokyo, 160-0023, Japan.
Hajime TanabeFaculty of Humanities and Social Sciences, Shizuoka University, Suruga-ku, Shizuoka, 422-8529, Japan.
Takeshi InoueDepartment of Psychiatry, Tokyo Medical University, Shinjuku-ku, Tokyo, 160-0023, Japan.ORCID 0000-0001-5248-1289
Tokyo Medical University · JPShizuoka University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWhen assessing patients with depressive and anxiety disorders in psychiatric clinical practice, it is common to encounter children and adolescents who have experienced abuse and victimization. To date, it has been clarified that experiences of "childhood abuse" and "childhood victimization" lead to "neuroticism", and that neuroticism leads to "adult depressive symptoms". In this study, we analyzed how these four factors are interrelated. SUBJECTS AND

methodsThe following self-administered questionnaire surveys were conducted in 576 adult volunteers: Patient Health Questionnaire-9, Eysenck Personality Questionnaire-revised shortened version, Child Abuse and Trauma Scale, and Childhood Victimization Rating Scale. For statistical analysis, Pearson correlation coefficient analysis,

resultsPath analysis showed that the indirect effects of childhood abuse and childhood victimization on depressive symptoms through neuroticism were statistically significant. In addition, the indirect effects of childhood abuse on neuroticism through childhood victimization were statistically significant. Finally, the indirect effects of childhood abuse on depressive symptoms through the combined paths of childhood victimization and neuroticism were statistically significant.

conclusionOur results suggest that "childhood abuse (A)" induces changes in the personality trait of "neuroticism (C)" with "childhood victimization (B)" as a mediator, and that these adversities affect the expression of "depressive symptoms in adulthood (D)" through "neuroticism (C)" as a mediator. In other words, to our knowledge, this is the first study to clarify that these four factors are not only individually associated with each other but also cause a chain reaction of A to B to C to D.

Indexed as

childhood abusechildhood victimizationdepressive symptomsneuroticismpath analysis

Identifiers

PMID35210773
PMCPMC8857998
OpenAlexW4213353156

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.