ArticleClinical ophthalmology (Auckland, N.Z.)2022
Evaluation of Microvascular and Visual Acuity Changes in Patients with Early Diabetic Retinopathy: Optical Coherence Tomography Angiography Study.
Article in Clinical ophthalmology (Auckland, N.Z.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 12 citations in OpenAlex.
- Outcome of pars plana vitrectomy with and without internal limiting membrane peeling in proliferative diabetic retinopathy.International ophthalmology · 2026Trial
- Relationship Between Foveal Avascular Zone Measured by Optical Coherence Tomography Angiography and Visual Acuity in Diabetic Retinopathy: A Systematic Review.Clinical ophthalmology (Auckland, N.Z.) · 2026Review
- Functional and structural biomarkers linked to diabetic retinal neurodegeneration in pre-clinical and early diabetic retinopathy.BMC ophthalmology · 2025Article
- Flow and ischemic changes in retina and choroid across diabetic retinopathy spectrum: a SS-OCTA study.Eye (London, England) · 2025Observational
- Quantitative analysis of peripapillary RNFL capillary density and thickness in patients with mild nonproliferative diabetic retinopathy.Frontiers in endocrinology · 2024Article
- Evaluation of Choroidal and Retinal Features in Patients with Primary Vasculitis-An Original Optical Coherence Tomography and Optical Coherence Tomography Angiography Study.Journal of clinical medicine · 2023Article
- Early changes to retinal structure in patients with diabetic retinopathy as determined by ultrawide swept-source optical coherence tomography-angiography.Frontiers in endocrinology · 2023Observational
- Schizophrenia in Translation: Why the Eye?Schizophrenia bulletin · 2022Article
- Effects of intensive insulin therapy on the retinal microvasculature in patients with type 2 diabetes mellitus: a prospective observational study.BMC ophthalmology · 2022Observational
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeComparison of early microvascular changes detected by optical coherence tomography angiography (OCTA) in patients with mild non-proliferative diabetic retinopathy (NPDR) with healthy volunteers. PATIENTS AND
methodsForty-four eyes of 44 type-2 diabetic patients with mild non-proliferative diabetic retinopathy and 30 eyes of 30 age-matched healthy controls were imaged using OCTA to quantify microvascular changes and the FAZ quantitative parameters (area, perimeter, and circularity index); the values of patients and controls were then compared.
resultsMacular vessel density, perfusion index, and circularity index values were reduced and positively correlated with visual acuity in patients (15.4 ± 2.6, 38.0 ± 6.7, 0.6 ± 0.06 and p = 0.003, 0.001, and 0.003, respectively). However, FAZ area and perimeter were found to be larger in patients than controls (0.30 ± 0.08, 2.5 ± 0.3 and p < 0.001).
conclusionOCTA quantified vessel density and perfusion density were found to be correlated with visual acuity and FAZ parameters in patients with early NPDR; this could help in detecting early disease progression and modifying treatment decisions.
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