ArticleScientific reports2022
Size fractionation of high-density polyethylene breakdown nanoplastics reveals different toxic response in Daphnia magna.
Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
6 citing papers in PubMed, 37 citations in OpenAlex.
- Generating Tagged Micro- and Nanoparticles of Poly(ethylene furanoate) and Poly(ethylene terephthalate) as Reference Materials.Macromolecular rapid communications · 2026Article
- Current Approaches to Microplastics Detection and Plastic Biodegradation.Molecules (Basel, Switzerland) · 2025Review
- Plastic Fly: WhatInternational journal of molecular sciences · 2024Article
- Size-Controlled Preparation of Polyethylene Nanoplastic Particles by Nanoprecipitation and Insights into the Underlying Mechanisms.ACS omega · 2023Article
- Prolonged survival time of Daphnia magna exposed to polylactic acid breakdown nanoplastics.PloS one · 2023Article
- Nanoplastics released from daily used silicone and latex products during mechanical breakdown.PloS one · 2023Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Plastic litter is a growing environmental problem. Recently, microplastics and nanoplastics, produced during breakdown processes in nature, have been in focus. Although there is a growing knowledge concerning microplastic, little is still known about the effect of nanoplastics. We have showed that mechanical breakdown of high-density polyethylene (HDPE), followed by filtration through 0.8 µm filters, produces material toxic to the freshwater zooplankton Daphnia magna and affected the reproduction in life-time tests. However, further size fractionation and purification reveals that the nanoplastics fraction is non-toxic at these concentrations, whereas the fraction with smaller sizes, below ~ 3 nm, is toxic. The HDPE nanoplastics are highly oxidized and with an average diameter of 110 nm. We conclude that mechanical breakdown of HDPE may cause environmental problems, but that the fraction of leached additives and short chain HDPE are more problematic than HDPE nanoplastics.
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Registered trials
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