Evidence map›Paper›PMID 35210335›Full record

Observational studyBMJ open2022

Association between multimorbidity, self-rated health and life satisfaction among independent, community-dwelling very old persons in Japan: longitudinal cohort analysis from the Kawasaki Ageing and Well-being Project.

Takayuki Ando, Yoshinori Nishimoto, Takumi Hirata, Yukiko Abe, Midori Takayama, Takashi Maeno, Seitaro Fujishima, Toru Takebayashi, Yasumichi Arai

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in BMJ open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 2 pooled it
5.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 2 syntheses or guidelines pooled it, 36 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Takayuki AndoCenter for General Medicine Education, Keio University School of Medicine, Shinjuku-ku, Tokyo, Japan.
Yoshinori NishimotoDepartment of Neurology, Keio University School of Medicine, Shinjuku-ku, Tokyo, Japan.
Takumi HirataDepartment of Public Health, Hokkaido University Graduate School of Medicine, Sapporo, Hokkaido, Japan.
Yukiko AbeCenter for Supercentenarian Medical Research, Keio University School of Medicine, Shinjuku-ku, Tokyo, Japan.
Midori TakayamaFaculty of Science and Technology, Keio University, Yokohama, Kanagawa, Japan.
Takashi MaenoGraduate School of System Design and Management, Keio University, Yokohama, Kanagawa, Japan.
Seitaro FujishimaCenter for General Medicine Education, Keio University School of Medicine, Shinjuku-ku, Tokyo, Japan.
Toru TakebayashiDepartment of Preventive Medicine and Public Health, Keio University School of Medicine, Shinjuku-ku, Tokyo, Japan.
Yasumichi AraiCenter for Supercentenarian Medical Research, Keio University School of Medicine, Shinjuku-ku, Tokyo, Japan yasumich@keio.jp.ORCID 0000-0003-1746-965X
Keio University · JPHokkaido University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study aimed to identify associations between multimorbidity and subjective health outcomes among the very old persons, after adjusting for coexisting conditions such as frailty and depression. STUDY SETTING AND

participantsThis was an observational cross-sectional study involving 1012 independent, community-dwelling very old persons (507 men, 505 women; aged 85-89 years) in Kawasaki city, Japan. OUTCOME MEASURES: The primary outcome was the cross-sectional associations between multimorbidity and poor self-rated health (SRH) and life satisfaction using binary logistic regression. The secondary outcome was the association of subjective health with each chronic condition.

resultsThe prevalence of multimorbidity (≥2 conditions) was 94.7%, and the average number of chronic conditions was 4.47±1.9. Multimorbidity was significantly associated with poor SRH in the adjusted model only when six or more chronic conditions were present (OR 4.80; 95% CI 1.34 to 17.11; p=0.016). Cerebrovascular disease, heart disease, respiratory disease, connective tissue disease and arthritis showed significant associations with poor SRH after multivariate adjustment. Sex-specific analysis replicated associations between multimorbidity with six or more conditions and SRH in both men and women, while the diseases with the greatest impact on SRH differed between men and women. Most conditions were not associated with low satisfaction with life scale, with the exception of arthritis (OR 1.92, 95% CI 1.32 to 2.78, p=0.001).

conclusionsMultimorbidity is prevalent in the independent, community-dwelling very old persons and is associated with poor SRH when six or more conditions are present; conditions causing mobility limitations, such as cerebrovascular disease, connective tissue disease and arthritis, have a negative impact on SRH. TRIAL REGISTRATION NUMBER: UMIN000026053.

Indexed as

Independent LivingMultimorbidityAged, 80 and overCohort StudiesCross-Sectional StudiesFemaleHealth StatusHumansJapanMalePersonal Satisfactionepidemiologygeneral medicine (see internal medicine)geriatric medicineprimary care

Identifiers

PMID35210335
PMCPMC8883229
OpenAlexW4213444967

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.