Evidence map›Paper›PMID 35210319›Full record

ArticleThe European respiratory journal2022

The burden of asthma, hay fever and eczema in adults in 17 countries: GAN Phase I study.

Kevin Mortimer, Maia Lesosky, Luis García-Marcos, M Innes Asher, Neil Pearce, Eamon Ellwood, Karen Bissell, Asma El Sony, Philippa Ellwood, Guy B Marks and 9 more

Open access · greenAbstract readClinical Trial, Phase I
In one paragraph

Article in The European respiratory journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 82 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
82citing papers in PubMed, 2 pooled it
16.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

82 citing papers in PubMed, 2 syntheses or guidelines pooled it, 151 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Observational
  4. From mild-to-moderate to severe asthma: risk factors and patient profiles from the NORDSTAR cohort.American journal of respiratory and critical care medicine · 2026
    Observational
  5. Worldwide Impact of Human Development and Inequality on the Prevalence of Asthma, Rhinoconjunctivitis and Eczema. Global Asthma Network's Ecological Study.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2026
    Article
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  8. Observational
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  13. Effect of initiation treatment timing on efficacy ofThe World Allergy Organization journal · 2026
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  20. Efficacy ofJournal of asthma and allergy · 2026
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22 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

19 authors at 8 institutions in 8 countries.

Kevin MortimerDept of Medicine, University of Cambridge, Cambridge, UK.
Maia LesoskyDept of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, UK.
Luis García-MarcosPaediatric Allergy and Pulmonology Units, Virgen de la Arrixaca University Children's Hospital, University of Murcia and IMIB Bio-health Research Institute, Murcia, Spain.ORCID 0000-0002-0925-3851
M Innes AsherDept of Paediatrics: Child and Youth Health, Faculty of Medical and Health Sciences, University of Auckland, Auckland, New Zealand.ORCID 0000-0003-1768-3832
Neil PearceDept of Medical Statistics, London School of Hygiene and Tropical Medicine, London, UK.
Eamon EllwoodDept of Paediatrics: Child and Youth Health, Faculty of Medical and Health Sciences, University of Auckland, Auckland, New Zealand.ORCID 0000-0003-2626-6619
Karen BissellSchool of Population Health, Faculty of Medical and Health Sciences, University of Auckland, Auckland, New Zealand.
Asma El SonyEpidemiological Laboratory (Epi-Lab) for Public Health, Research and Development, Khartoum, Sudan.ORCID 0000-0002-6989-8862
Philippa EllwoodDept of Paediatrics: Child and Youth Health, Faculty of Medical and Health Sciences, University of Auckland, Auckland, New Zealand.ORCID 0000-0002-1994-4023
Guy B MarksRespiratory and Environmental Epidemiology, University of New South Wales, Sydney, Australia.ORCID 0000-0002-8976-8053
Antonela Martínez-TorresPaediatric Allergy and Pulmonology Units and Nurse Research Group, Virgen de la Arrixaca University Children's Hospital, Murcia, Spain.
Eva MoralesDept of Public Health Sciences, University of Murcia and IMIB Bio-health Research Institute, Edificio Departamental-LAIB, Murcia, Spain.
Virginia Perez-FernandezDept of Biostatistics, University of Murcia and IMIB Bio-health Research Institute, Edificio Departamental-LAIB, Murcia, Spain.ORCID 0000-0003-1877-3055
Steven RobertsonDept of Medical Statistics, London School of Hygiene and Tropical Medicine, London, UK.
Charlotte E RutterDept of Medical Statistics, London School of Hygiene and Tropical Medicine, London, UK.
Richard J SilverwoodDept of Medical Statistics, London School of Hygiene and Tropical Medicine, London, UK.ORCID 0000-0002-2744-1194
David P StrachanPopulation Health Research Institute, St George's, University of London, London, UK.
Chen-Yuan ChiangInternational Union Against Tuberculosis and Lung Disease, Paris, France cychiang@tmu.edu.tw.ORCID 0000-0002-9291-2490
Global Asthma Network Phase I Study Group
Instituto Murciano de Investigación Biosanitaria · ESUniversity of Auckland · NZUniversity of London · GBInternational Union Against Tuberculosis and Lung Disease · FRSt George's, University of London · GBUniversity of Cape Town · ZAUniversity of Liverpool · GBUNSW Sydney · AU

Funding

Medical Research Council MR/N013638/1
6 · The paper itself

Abstract

aimsAsthma, hay fever and eczema are three common chronic conditions. There have been no recent multi-country data on the burden of these three conditions in adults; the aims of this study are to fill this evidence gap.

methodsThe Global Asthma Network Phase I is a multi-country cross-sectional population-based study using the same core methodology as the International Study of Asthma and Allergies in Childhood Phase III. It provides data on the burden of asthma, hay fever and eczema in children and adolescents, and, for the first time, in their parents/guardians.

resultsData were available from 193 912 adults (104 061 female; mean±sd age 38±7.5 years) in 43 centres in 17 countries. The overall prevalence (range) of symptoms was 6.6% (0.9-32.7%) for current wheeze, 4.4% (0.9-29.0%) for asthma ever, 14.4% (2.8-45.7%) for hay fever ever and 9.9% (1.6-29.5%) for eczema ever. Centre prevalence varied considerably both between countries and within countries. There was a moderate correlation between hay fever ever and asthma ever, and between eczema ever and hay fever ever at the centre level. There were moderate to strong correlations between indicators of the burden of disease reported in adults and the two younger age groups.

conclusionWe found evidence for a substantial burden of asthma, hay fever ever and eczema ever in the countries examined, highlighting the major public health importance of these diseases. Prevention strategies and equitable access to effective and affordable treatments for these three conditions would help mitigate the avoidable morbidity they cause.

Indexed as

AsthmaEczemaRhinitis, Allergic, SeasonalAdolescentAdultChildCross-Sectional StudiesFemaleHumansMiddle AgedPrevalenceSurveys and Questionnaires

Identifiers

PMID35210319
PMCPMC9474894
OpenAlexW4213454188

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.