Evidence map›Paper›PMID 35210301›Full record

ArticleJournal of nuclear medicine : official publication, Society of Nuclear Medicine2022

Cardiac Fibroblast Activation in Patients Early After Acute Myocardial Infarction: Integration with MR Tissue Characterization and Subsequent Functional Outcome.

Johanna Diekmann, Tobias Koenig, James T Thackeray, Thorsten Derlin, Christoph Czerner, Jonas Neuser, Tobias L Ross, Andreas Schäfer, Jochen Tillmanns, Johann Bauersachs and 1 more

Registry-linked trialOpen access · bronzeAbstract read
In one paragraph

Article in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06945549 (Evaluation of Intestinal Lesions and Disease Activity in Inflammatory Bowel Disease Based on 18F-FAPI PET Imaging), which is not on this map. Cited by 63 papers.

0numbers the graph read from it
0cells of the map it votes in
63citing papers in PubMed
10.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06945549 recruitingnot on this mapstarted 2025, after this paper: background citation

Evaluation of Intestinal Lesions and Disease Activity in Inflammatory Bowel Disease Based on 18F-FAPI PET Imaging

TypeobservationalSponsorDaping Hospital and the Research Institute of Surgery of the Third Military Medical UniversityRan2025 to 2027Enrolled30ConditionsInflammatory Bowel Disease (IBD), Disease Activity, FAPIArms18F-FAPI PET Imaging
3 · Its place in the literature

Who cites it

63 citing papers in PubMed, 104 citations in OpenAlex.

  1. Multi-modality deep learning-based [European journal of nuclear medicine and molecular imaging · 2024
    Trial
  2. Review
  3. Early post-infarct fibroblast activation protein-targeted PET/CT withEuropean journal of nuclear medicine and molecular imaging · 2026
    Article
  4. Coronary artery disease imaging with total-body PET.The British journal of radiology · 2026
    Review
  5. Next-generation molecular imaging of cardiac fibrosis.The international journal of cardiovascular imaging · 2026
    Review
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Molecular Imaging of Collagen Turnover in Myocardial Infarction.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2026
    Article
  12. Review
  13. Review
  14. Article
  15. Preclinical Evaluation ofJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2026
    Article
  16. Review
  17. Article
  18. Article
  19. Total-body positron emission tomography: Investigating mechanisms in cardiovascular-kidney-metabolic syndrome.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2025
    Review
  20. Review

3 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Johanna DiekmannDepartment of Nuclear Medicine, Hannover Medical School, Hannover, Germany; and bengel.frank@mh-hannover.de diekmann.johanna@mh-hannover.de.
Tobias KoenigDepartment of Cardiology and Angiology, Hannover Medical School, Hannover, Germany.
James T ThackerayDepartment of Nuclear Medicine, Hannover Medical School, Hannover, Germany; and.
Thorsten DerlinDepartment of Nuclear Medicine, Hannover Medical School, Hannover, Germany; and.
Christoph CzernerDepartment of Nuclear Medicine, Hannover Medical School, Hannover, Germany; and.
Jonas NeuserDepartment of Cardiology and Angiology, Hannover Medical School, Hannover, Germany.
Tobias L RossDepartment of Nuclear Medicine, Hannover Medical School, Hannover, Germany; and.
Andreas SchäferDepartment of Cardiology and Angiology, Hannover Medical School, Hannover, Germany.
Jochen TillmannsDepartment of Cardiology and Angiology, Hannover Medical School, Hannover, Germany.
Johann BauersachsDepartment of Cardiology and Angiology, Hannover Medical School, Hannover, Germany.
Frank M BengelDepartment of Nuclear Medicine, Hannover Medical School, Hannover, Germany; and bengel.frank@mh-hannover.de diekmann.johanna@mh-hannover.de.
Medizinische Hochschule Hannover · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

After acute myocardial infarction (AMI), fibroblast activation protein (FAP) upregulation exceeds the infarct region. We sought further insights into the physiologic relevance by correlating FAP-targeted PET with tissue characteristics from cardiac MRI (CMR) and functional outcome.

Indexed as

Magnetic Resonance Imaging, CineMyocardial InfarctionContrast MediaFibroblastsGadoliniumGallium RadioisotopesHumansMyocardiumPositron Emission Tomography Computed TomographyPredictive Value of TestsStroke VolumeVentricular Function, LeftContrast MediaGadoliniumGallium Radioisotopesfibroblast activation proteinleft ventricular remodelingmyocardial infarctionPET

Identifiers

PMID35210301
PMCPMC9454470
OpenAlexW4214714238

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.