Evidence map›Paper›PMID 35209911›Full record

Trial reportHealth and quality of life outcomes2022

Effect of aerobic exercise intensity on health-related quality of life in severe obesity: a randomized controlled trial.

Jarle Berge, Jøran Hjelmesæth, Ronette L Kolotkin, Øyvind Støren, Solfrid Bratland-Sanda, Jens Kristoffer Hertel, Espen Gjevestad, Milada Cvancarova Småstuen, Jan Helgerud, Tomm Bernklev

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Health and quality of life outcomes, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02311738 (The Effect of Exercise and Genes on Energy Expenditure, Appetite and Quality of Life in Morbidly Obese Patients), which is not on this map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
7.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02311738 naunknown statusnot on this map

The Effect of Exercise and Genes on Energy Expenditure, Appetite and Quality of Life in Morbidly Obese Patients

TypeinterventionalSponsorJarle BergeRan2015 to 2023Enrolled50ConditionsObesityArmsTraining intensity intervention
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Jarle BergeMorbid Obesity Centre, Vestfold Hospital Trust, Box 2168, 3103, Tønsberg, Norway. Jarle.berge@siv.no.ORCID http://orcid.org/0000-0001-9188-6043
Jøran HjelmesæthMorbid Obesity Centre, Vestfold Hospital Trust, Box 2168, 3103, Tønsberg, Norway.
Ronette L KolotkinMorbid Obesity Centre, Vestfold Hospital Trust, Box 2168, 3103, Tønsberg, Norway.
Øyvind StørenNature, Health and Environment, University of South-Eastern Norway, Bø, Norway.
Solfrid Bratland-SandaDepartment of Sport, Physical Education and Outdoor Life Studies, University of South-Eastern Norway, Bø, Norway.
Jens Kristoffer HertelMorbid Obesity Centre, Vestfold Hospital Trust, Box 2168, 3103, Tønsberg, Norway.
Espen GjevestadClinic of Medicine and Rehabilitation, Vestfold Hospital Trust, Stavern, Norway.
Milada Cvancarova SmåstuenMorbid Obesity Centre, Vestfold Hospital Trust, Box 2168, 3103, Tønsberg, Norway.
Jan HelgerudDepartment of Circulation and Medical Imaging, Faculty of Medicine and Health Science, Norwegian University of Science and Technology, Trondheim, Norway.
Tomm BernklevFaculty of Medicine, Institute for Clinical Medicine, University of Oslo, Oslo, Norway.
Sykehuset i Vestfold · NONorwegian Police University College · NOUniversity of Oslo · NOUniversity of South-Eastern Norway · NONorwegian University of Science and Technology · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAerobic exercise is an important part of obesity treatment and may improve health-related quality of life (HRQOL). The objective of this study was to compare the effect of two different exercise programs on health-related quality of life in patients with severe obesity.

methodsThis was a single-center, open-label, randomized, parallel-group study comparing the effects of a 24-week moderate-intensity continuous training (MICT) program and a combined high-intensity interval training program with MICT (HIIT/MICT). The primary objective (specified secondary outcome) was to assess HRQOL by using the general health dimension of the Short Form Health Survey (SF-36). The secondary objectives were to assess other dimensional SF-36 scores, the impact of weight on the physical and psychosocial aspects of quality of life (IWQOL-Lite), and the burden of obesity-specific weight symptoms (WRSM).

results73 patients were enrolled and reported patient reported outcome measures, with 71 patients (55% females) allocated to either MICT (n = 34) or HIIT/MICT (n = 37). In the intention-to-treat analysis, general health scores increased between baseline and 24-week follow-up in both the HIIT/MICT group and the MICT group, with a mean change of 13 (95% CI 6-21) points and 11 (95% CI 5-17) points, respectively, with no difference between the groups. The effect sizes of these changes were moderate. The vitality and social functioning scores of SF-36, and the physical function and self-esteem scores of IWQOL-Lite increased moderately in both groups, with no difference between groups. The tiredness, back pain, and physical stamina scores based on WRSM showed moderate to strong changes in both the groups.

conclusionsPatients who had completed a combined HIIT/MICT program did not experience larger improvements in general health compared with those completing a clean 24-week MICT program. Exercise may confer general health benefits independent of intensity. TRIALS REGISTRATION: Regional Committees for Medical and Health Research Ethics south east, Norway, October 23, 2013 (identifier: 2013/1849) and ClinicalTrials.gov December 8, 2014 (identifier: NCT02311738).

Indexed as

High-Intensity Interval TrainingObesity, MorbidExerciseFemaleHumansMaleObesityQuality of LifeAerobic exerciseHealth-related quality of lifeSevere obesityVO2max

Identifiers

PMID35209911
PMCPMC8876087
OpenAlexW4213453104

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.