Evidence map›Paper›PMID 35209908›Full record

ArticleJournal of nanobiotechnology2022

The sustained PGE

Haoyan Huang, Shang Chen, Hui Cheng, Jiasong Cao, Wei Du, Jun Zhang, Yuqiao Chang, Xiaohong Shen, Zhikun Guo, Zhibo Han and 5 more

Open access · goldAbstract read
In one paragraph

Article in Journal of nanobiotechnology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.3field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. Article
  3. Prostaglandin EEXCLI journal · 2025
    Review
  4. Article
  5. Article
  6. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 2 countries.

Haoyan HuangNankai University School of Medicine, Tianjin, China.
Shang ChenNankai University School of Medicine, Tianjin, China.
Hui ChengNankai University School of Medicine, Tianjin, China.
Jiasong CaoTianjin Key Laboratory of Human Development and Reproductive Regulation, Tianjin Central Hospital of Gynecology Obstetrics, Nankai University Affiliated Hospital of Obstetrics and Gynecology, Tianjin, China.
Wei DuTianjin Key Laboratory of Blood Cell Therapy Technology, Union Stem Cell & Gene Engineering Co. Ltd., Tianjin, China.
Jun ZhangDepartment of Pain Treatment, Tianjin Union Medical Center, Nankai University Affiliated Hospital, Tianjin, China.
Yuqiao ChangHenan Key Laboratory of Medical Tissue Regeneration, Xinxiang Medical University, Xinxiang, China.
Xiaohong ShenNankai University School of Medicine, Tianjin, China.
Zhikun GuoHenan Key Laboratory of Medical Tissue Regeneration, Xinxiang Medical University, Xinxiang, China.
Zhibo HanTianjin Key Laboratory of Engineering Technologies for Cell Pharmaceutical, National Engineering Research Center for Cell Products, AmCellGene Co., Ltd., Tianjin, China.
Guoqiang HuaINSERM (French Institute of Health and Medical Research), UMR 1260, Regenerative Nanomedicine (RNM), FMTS, Strasbourg, France.
Zhong-Chao HanTianjin Key Laboratory of Engineering Technologies for Cell Pharmaceutical, National Engineering Research Center for Cell Products, AmCellGene Co., Ltd., Tianjin, China.
Nadia Benkirane-JesselINSERM (French Institute of Health and Medical Research), UMR 1260, Regenerative Nanomedicine (RNM), FMTS, Strasbourg, France.
Ying ChangTianjin Key Laboratory of Human Development and Reproductive Regulation, Tianjin Central Hospital of Gynecology Obstetrics, Nankai University Affiliated Hospital of Obstetrics and Gynecology, Tianjin, China. changying4470@126.com.
Zongjin LiNankai University School of Medicine, Tianjin, China. zongjinli@nankai.edu.cn.ORCID http://orcid.org/0000-0002-4603-3743
Nankai University · CNInserm · FRTianjin Central Hospital of Gynecology Obstetrics · CNXinxiang Medical University · CN

Funding

National Key R&D Program of China 2017YFA0103200National Natural Science Foundation of China U2004126Tianjin Science and Technology Plan Innovation Platform Special Support Program 18PTSYJC00070
6 · The paper itself

Abstract

backgroundThe promising therapeutic strategy for the treatment of peripheral artery disease (PAD) is to restore blood supply and promote regeneration of skeletal muscle regeneration. Increasing evidence revealed that prostaglandin E

resultsIn this study, we designed and synthesized a new PGE

conclusionsOur findings highlight the chemical bonding strategy of chemical bonding PGE

Indexed as

DinoprostoneNeovascularization, PhysiologicAnimalsDisease Models, AnimalHindlimbIschemiaMuscle, SkeletalDinoprostoneAngiogenesisHindlimb ischemia (HI)Molecular imagingMuscle regenerationMyoD1Prostaglandin E2 (PGE2)Sustained release

Identifiers

PMID35209908
PMCPMC8867652
OpenAlexW4213422520

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.