SynthesisBMC neurology2022
Intra-cerebellar schwannoma with various degenerative changes: a case report and a systematic review.
Synthesis in BMC neurology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- VGLL-fused intraparenchymal schwannoma with EWSR1::VGLL1 fusion: integrated clinicopathological and molecular characterization.Acta neuropathologica communications · 2026Article
- MRI findings for the pretreatment diagnosis of small Meckel's cave tumors: comparison of meningiomas and schwannomas.BMC medical imaging · 2025Article
- Clinical and radiological features of intracranial ancient schwannomas: a single-institution, retrospective analysis.Brain tumor pathology · 2024Article
- A Rare Presentation of Intracerebellar Schwannoma: A Case Report.Case reports in pathology · 2024Article
- Case Report: Adrenal glands degenerated schwannoma: Report of three cases and literature review.Frontiers in oncology · 2023Article
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8 authors.
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Abstract
backgroundIntra-cranial schwannomas account for less than 8% of brain tumors, among which more than 80% arise from the vestibular nerve. Intra-cerebellar schwannomas are extremely rare. Several cases have been previously reported but without remarkable degenerative changes on histology. CASE PRESENTATION: A 61-year-old man presented with worsening disorientation, and an imaging study revealed a cystic lesion (6.5 cm in the largest diameter) in the left hemisphere of the cerebellum accompanied by a mural nodule (2.5 cm) located just inside the skull with enhancement and focal calcification, in addition to hydrocephalus. The lesion was more than 5 mm from the left acoustic nerve. The patient underwent gross total resection. Pathological examination revealed remarkable degenerative changes with various morphological features. Tumor cells were pleomorphic with rich cytoplasm containing numerous eosinophilic granules. Blood vessels and extracellular matrix showed remarkable hyalinization. Immunohistochemical staining revealed that the tumor cells were positive for S-100 protein and negative for Olig2. The tumor was diagnosed as a schwannoma with marked degenerative changes.
conclusionsThe present case is discussed with reference to a systematic review of previous reports of intra-cerebellar schwannoma. Intra-cerebellar schwannoma should be included in the differential diagnosis of cystic lesions with heterogeneous histopathological morphology in the cerebellum.
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