Evidence map›Paper›PMID 35209754›Full record

SynthesisVascular medicine (London, England)2022

What is the impact of aerobic fitness and movement interventions on low-flow-mediated vasoconstriction? A systematic review of observational and intervention studies.

Myles W O'Brien, Jennifer L Petterson, Yanlin Wu, Nick W Bray, Derek S Kimmerly

Open access · greenAbstract readSystematic Review
In one paragraph

Synthesis in Vascular medicine (London, England), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Myles W O'BrienDivision of Kinesiology, Dalhousie University, Halifax, NS, Canada.ORCID 0000-0002-0665-5062
Jennifer L PettersonDivision of Kinesiology, Dalhousie University, Halifax, NS, Canada.
Yanlin WuDivision of Kinesiology, Dalhousie University, Halifax, NS, Canada.
Nick W BrayFaculty of Professional Studies, School of Kinesiology, Acadia University, Wolfville, NS, Canada.
Derek S KimmerlyDivision of Kinesiology, Dalhousie University, Halifax, NS, Canada.ORCID 0000-0002-3462-8037
Dalhousie University · CAAcadia University · CA

Funding

CIHR
6 · The paper itself

Abstract

The cardiovascular benefits of physical exercise are well established. The vasoreactivity that occurs during reductions in local arterial blood flow, termed low-flow-mediated constriction (L-FMC), is a measure of endothelial-dependent vasoconstrictor function. It is unclear whether aerobic fitness and movement (or lack thereof) influences L-FMC. We systematically reviewed studies examining the impact of physical behaviours on L-FMC. To be included, cross-sectional and interventional studies had to examine the impact of a physical behaviour on L-FMC in adults. There were no language or date of publication restrictions. Sources were searched in May, 2021 and included Scopus, Embase, MEDLINE, CINAHL, and Academic Search Premier. National Institutes of Health quality assessment tools were used. Fourteen studies (15 arms; 313 participants; 398 total observations from four arteries) met the inclusion criteria. The study quality varied from four out of 14 (controlled intervention scoring) to nine out of 12 (longitudinal intervention with no control group scoring) with the total points dependent upon the study design. Conflicting results were reported for acute prolonged sitting studies (attenuated L-FMC:

Indexed as

ExerciseVasoconstrictionAdultCross-Sectional StudiesHumansRegional Blood FlowVasoconstrictor AgentsVasoconstrictor Agentsaerobic fitnessendothelial functionprolonged sittingresistance exercisevasoconstrictor function

Identifiers

PMID35209754
PMCPMC11909780
OpenAlexW4214526174

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.