Evidence map›Paper›PMID 35209742›Full record

ArticleThe Journal of international medical research2022

Mortality and associated risk factors in patients with severe methanol or ethylene glycol poisoning treated with dialysis: a retrospective cohort study.

Emma Kuusela, Mikko J Järvisalo, Tapio Hellman, Panu Uusalo

Open access · goldAbstract read
In one paragraph

Article in The Journal of international medical research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.8field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Emma KuuselaDepartment of Anaesthesiology and Intensive Care, Turku University Hospital and University of Turku, Turku, Finland.ORCID https://orcid.org/0000-0001-7737-1270
Mikko J JärvisaloDepartment of Anaesthesiology and Intensive Care, Turku University Hospital and University of Turku, Turku, Finland.ORCID https://orcid.org/0000-0002-0507-2148
Tapio HellmanKidney Center, Turku University Hospital and University of Turku, Turku, Finland.
Panu UusaloDepartment of Anaesthesiology and Intensive Care, Turku University Hospital and University of Turku, Turku, Finland.ORCID https://orcid.org/0000-0001-5120-8854
University of Turku · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo compare the initial clinical course and data on 90-day mortality in adults with methanol (MET) or ethylene glycol (EG) poisoning treated with dialysis.

methodsData on patient demographics and clinical parameters at intensive care unit (ICU) admission and for the first 24 hours after dialysis initiation were collected, and 90-day outcome data were collected for patients with MET (n = 15) or EG (n = 13) poisoning treated with dialysis in this retrospective cohort study.

resultsIn univariate analysis, patients with EG poisoning were older and they had lower hourly urine output during the first 24 hours after the initiation of dialysis. Six (46%) patients with MET poisoning and three (20%) patients with EG poisoning died within 90 days of ICU admission. A larger anion gap and lower pH, bicarbonate levels, base excess, and Glasgow Coma Scale scores on admission, as well as the need for mechanical ventilation, were associated with 90-day mortality.

conclusionsMetabolic acidosis, a large anion gap, and an altered mental status on admission appear to be associated with mortality in MET or EG poisoning, and EG poisoning may be linked to lower urine output.

Indexed as

Ethylene GlycolMethanolAdultHumansRenal DialysisRetrospective StudiesRisk FactorsEthylene GlycolMethanolanion gapbicarbonateethylene glycolmetabolic acidosisMethanolpoisoningrenal replacement therapy

Identifiers

PMID35209742
PMCPMC8891871
OpenAlexW4214676887

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.