ArticleEpidemiology and health2022
Recent trends in opioid prescriptions in Korea from 2002 to 2015 based on the Korean NHIS-NSC cohort.
Article in Epidemiology and health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 12 citations in OpenAlex.
- Regional Trends in the Opioid Epidemic Using Safety Signals of Drug Abuse and Dependence: A Disproportionality Analysis Using VigiBase.Drugs - real world outcomes · 2026Article
- Perioperative use of fentanyl and tramadol in pediatric distal humerus fractures: a 15-year retrospective cohort study in Korea.Scientific reports · 2025Article
- Potentially Inappropriate Use of Transdermal Fentanyl in Working-Age and Older Adult Populations with Non-Cancer Pain: Nationwide Cross-Sectional Study.JMIR public health and surveillance · 2025Article
- The Impact of Opioid Prescription on the Occurrence and Outcome of Pneumonia: A Nationwide Cohort Study in South Korea.Respiratory care · 2024Article
- Assessment of Epidemiological Data and Surveillance in Korea Substance Use Research: Insights and Future Directions.Journal of preventive medicine and public health = Yebang Uihakhoe chi · 2024Review
- Early Hospice Consultation Team Engagement for Cancer Pain Relief: A Case Report.Journal of hospice and palliative care · 2024Article
- Opioid Prescription and Long-Term Survival Outcomes in Adults: A Nationwide Cohort Study in Korea.Journal of Korean medical science · 2024Article
- Current status of opioid prescription in South Korea using narcotics information management system.The Korean journal of pain · 2024Article
- Prevention, diagnosis, and treatment of opioid use disorder under the supervision of opioid stewardship programs: it's time to act now.The Korean journal of pain · 2022Review
- Economic burden of opioid misuse focused on direct medical costs.Frontiers in pharmacology · 2022Article
Corrections and comments
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Authors and funding
9 authors at 4 institutions in 1 country.
Funding
Abstract
objectivesOpioids are prescribed to treat moderate to severe pain. We investigated recent trends in opioid (morphine, oxycodone, fentanyl, and hydromorphone) prescriptions using data from the Korean National Health Insurance Service-National Sample Cohort between 2002 and 2015.
methodsThe morphine milligram equivalent (MME) was calculated to standardize the relative potency of opioids. The number (cases) or amount (MME) of annual opioid prescriptions per 10,000 registrants was computed to analyze trends in opioid prescriptions after age standardization. Joinpoint regression analysis was conducted to calculate the annual percentage change and average annual percentage change (AAPC).
resultsThe number (cases) of prescriptions per 10,000 registrants increased from 0.07 in 2002 to 41.23 in 2015 (AAPC, 76.0%; 95% confidence interval [CI], 61.6 to 91.7). The MME per 10,000 registrants increased from 15.06 in 2002 to 40,727.80 in 2015 (AAPC, 103.0%; 95% CI, 78.2 to 131.3). The highest AAPC of prescriptions and MME per 10,000 registrants were observed in the elderly (60-69 years) and in patients treated at general hospitals. Fentanyl prescriptions increased most rapidly among the 4 opioids.
conclusionsConsumption of opioids greatly increased in Korea over the 14-year study period.
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