Evidence map›Paper›PMID 35209213›Full record

ArticleMolecules (Basel, Switzerland)2022

Multilayered Curcumin-Loaded Hydrogel Microcarriers with Antimicrobial Function.

Weronika Szczęsna, Marta Tsirigotis-Maniecka, Łukasz Lamch, Lilianna Szyk-Warszyńska, Ewa Zboińska, Piotr Warszyński, Kazimiera A Wilk

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Weronika SzczęsnaDepartment of Engineering and Technology of Chemical Processes, Faculty of Chemistry, Wrocław University of Science and Technology, 50-370 Wrocław, Poland.
Marta Tsirigotis-ManieckaDepartment of Engineering and Technology of Chemical Processes, Faculty of Chemistry, Wrocław University of Science and Technology, 50-370 Wrocław, Poland.ORCID 0000-0002-0764-0751
Łukasz LamchDepartment of Engineering and Technology of Chemical Processes, Faculty of Chemistry, Wrocław University of Science and Technology, 50-370 Wrocław, Poland.ORCID 0000-0002-0332-7119
Lilianna Szyk-WarszyńskaJerzy Haber Institute of Catalysis and Surface Chemistry, Polish Academy of Sciences, 30-239 Kraków, Poland.ORCID 0000-0002-2950-3459
Ewa ZboińskaDepartment of Organic and Medicinal Chemistry, Faculty of Chemistry, Wrocław University of Science and Technology, 50-370 Wrocław, Poland.
Piotr WarszyńskiJerzy Haber Institute of Catalysis and Surface Chemistry, Polish Academy of Sciences, 30-239 Kraków, Poland.ORCID 0000-0001-5449-9060
Kazimiera A WilkDepartment of Engineering and Technology of Chemical Processes, Faculty of Chemistry, Wrocław University of Science and Technology, 50-370 Wrocław, Poland.ORCID 0000-0002-2020-1761

Funding

Ministry of Science and Higher Education Statutory funding for Jerzy Haber Institute of Catalysis and Surface Chemistry PASMinistry of Science and Higher Education Statutory funding for the Faculty of Chemistry of the Wrocław University of Science and TechnologyNational Science Center 2017/25/B/ST4/02450
6 · The paper itself

Abstract

The design of multifunctional microcarriers has attracted significant attention because they combine various functions within a single system. In this study, we developed a set of multilayered hydrogel microcarriers, which were first loaded with chemotherapeutic curcumin (CUR), then, using the layer-by-layer (LbL) technique, coated through a polyelectrolyte shell consisting of chitosan (CHIT) or poly(allylamine hydrochloride) (PAH). As an outer layer with antimicrobial function, newly synthesised alkylene quaternary ammonium salt functionalised polyelectrolytes (A-QAS-PEs) were applied. For this purpose, poly(acrylic acid) (PAA) was decorated with different hydrophobic side chains (

Indexed as

Anti-Bacterial AgentsCurcuminDrug CarriersHydrogelsSerratia marcescensStaphylococcus aureusAnti-Bacterial AgentsCurcuminDrug CarriersHydrogelsantimicrobial functioncurcumindecorated poly(acrylic acid)layer-by-layer (LbL) methodologymultifunctional microcarriers

Identifiers

PMID35209213
PMCPMC8875356

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.