Evidence map›Paper›PMID 35209189›Full record

ArticleMolecules (Basel, Switzerland)2022

In Vivo Antistress Effects of Synthetic Flavonoids in Mice: Behavioral and Biochemical Approach.

Mehreen Ghias, Syed Wadood Ali Shah, Fakhria A Al-Joufi, Mohammad Shoaib, Syed Muhammad Mukarram Shah, Muhammad Naeem Ahmed, Muhammad Zahoor

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Preparing a novel baicalin-loaded microemulsion-based gel for transdermal delivery and testing its anti-gout effect.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Mehreen GhiasDepartment of Pharmacy, University of Malakand, Dir (Lower), Chakdara 18800, Khyber Pakhtunkhwa, Pakistan.
Syed Wadood Ali ShahDepartment of Pharmacy, University of Malakand, Dir (Lower), Chakdara 18800, Khyber Pakhtunkhwa, Pakistan.ORCID 0000-0001-8143-2363
Fakhria A Al-JoufiDepartment of Pharmacology, College of Pharmacy, Jouf University, Aljouf 72341, Saudi Arabia.ORCID 0000-0002-7223-9788
Mohammad ShoaibDepartment of Pharmacy, University of Malakand, Dir (Lower), Chakdara 18800, Khyber Pakhtunkhwa, Pakistan.
Syed Muhammad Mukarram ShahDepartment of Pharmacy, University of Swabi, Swabi 23460, Khyber Pakhtunkhwa, Pakistan.
Muhammad Naeem AhmedDepartment of Chemistry, The University of Azad Jammu and Kashmir, Muzaffarabad 13100, Pakistan.ORCID 0000-0002-5559-1763
Muhammad ZahoorDepartment of Biochemistry, University of Malakand, Dir (Lower), Chakdara 18800, Khyber Pakhtunkhwa, Pakistan.ORCID 0000-0002-4528-8517
University of Malakand · PKUniversity of Swabi · PKJouf University · SAUniversity of Azad Jammu and Kashmir · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Natural flavonoids, in addition to some of their synthetic derivatives, are recognized for their remarkable medicinal properties. The present study was designed to investigate the in vitro antioxidant and in vivo antistress effect of synthetic flavonoids (flavones and flavonols) in mice, where stress was induced by injecting acetic acid and physically through swimming immobilization. Among the synthesized flavones (

Indexed as

AnimalsAntioxidantsBehavior, AnimalBiomarkersFlavonesFlavonoidsFlavonolsMiceReactive Oxygen SpeciesStress, PhysiologicalStress, PsychologicalAntioxidantsBiomarkersFlavonesFlavonoidsFlavonolsReactive Oxygen Speciesantioxidantbiomarkersflavones and flavonolsin vivo studystress

Identifiers

PMID35209189
PMCPMC8879959
OpenAlexW4214632622

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.