Evidence map›Paper›PMID 35209156›Full record

ArticleMolecules (Basel, Switzerland)2022

Machine Learning Analysis of Essential Oils from Cuban Plants: Potential Activity against Protozoa Parasites.

Renata Priscila Barros de Menezes, Luciana Scotti, Marcus Tullius Scotti, Jesús García, Rosalia González, Lianet Monzote, William N Setzer

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Renata Priscila Barros de MenezesPost-Graduate Program in Natural and Synthetic Bioactive Products, Federal University of Paraíba, João Pessoa 58051-900, Brazil.
Luciana ScottiPost-Graduate Program in Natural and Synthetic Bioactive Products, Federal University of Paraíba, João Pessoa 58051-900, Brazil.ORCID 0000-0003-1866-4107
Marcus Tullius ScottiPost-Graduate Program in Natural and Synthetic Bioactive Products, Federal University of Paraíba, João Pessoa 58051-900, Brazil.ORCID 0000-0003-4863-8057
Jesús GarcíaPharmacy Department, Faculty of Natural and Exact Sciences, University of Oriente, Santiago de Cuba 90500, Cuba.ORCID 0000-0003-2309-3417
Rosalia GonzálezToxicology and Biomedicine Centre (TOXIMED), University of Medical Science, Santiago de Cuba 90500, Cuba.
Lianet MonzoteParasitology Department, Institute of Tropical Medicine "Pedro Kouri", Havana 10400, Cuba.ORCID 0000-0002-1958-809X
William N SetzerAromatic Plant Research Center, 230 N 1200 E, Suite 100, Lehi, UT 84043, USA.ORCID 0000-0002-3639-0528

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Essential oils (EOs) are a mixture of chemical compounds with a long history of use in food, cosmetics, perfumes, agricultural and pharmaceuticals industries. The main object of this study was to find chemical patterns between 45 EOs and antiprotozoal activity (antiplasmodial, antileishmanial and antitrypanosomal), using different machine learning algorithms. In the analyses, 45 samples of EOs were included, using unsupervised Self-Organizing Maps (SOM) and supervised Random Forest (RF) methodologies. In the generated map, the hit rate was higher than 70% and the results demonstrate that it is possible find chemical patterns using a supervised and unsupervised machine learning approach. A total of 20 compounds were identified (19 are terpenes and one sulfur-containing compound), which was compared with literature reports. These models can be used to investigate and screen for bioactivity of EOs that have antiprotozoal activity more effectively and with less time and financial cost.

Indexed as

Machine LearningAntiprotozoal AgentsCubaDatabases, FactualOils, VolatileParasitic Sensitivity TestsPlant OilsAntiprotozoal AgentsOils, VolatilePlant Oilsantiprotozoal activityCuban plantsessential oilmachine learning analysis

Identifiers

PMID35209156
PMCPMC8878085

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.