ArticleMolecules (Basel, Switzerland)2022
Implementation of an Analytical Method for Spectrophotometric Evaluation of Total Phenolic Content in Essential Oils.
Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed, 52 citations in OpenAlex.
- Physicochemical, Phytochemical, and Toxicological Assessment ofMolecules (Basel, Switzerland) · 2026Article
- Phytochemical Characterisation, antioxidant, anti-inflammatory, antibacterial, antibiofilm, anticancer properties and therapeutic potentials of Eucalyptus globulus essential oil.Scientific reports · 2026Article
- Application ofPolymers · 2026Article
- Neuro-protective Potential of Honey: A Narrative Review.Current pharmaceutical design · 2026Review
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- In Vitro and in Vivo Efficacy of Different Ointment Formulations ContainingPharmaceuticals (Basel, Switzerland) · 2025Article
- Effects of Electromagnetically Treated Water (EMTW) on the Properties of Water and Photosynthetic Performance ofPlants (Basel, Switzerland) · 2025Article
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- Potential Applications ofFood science & nutrition · 2025Article
- Enhancing antioxidant activity and quality ofFrontiers in nutrition · 2025Article
- Comparative Evaluation of Camelina Seed Oils Obtained by Cold-Pressing and Solvent Extraction.Foods (Basel, Switzerland) · 2024Article
- Essential Oils ofFoods (Basel, Switzerland) · 2024Article
- Revolutionizing Phenolic Content Determination in Vegetable Oils: A Cutting-Edge Approach Using Smartphone-Based Image Analysis.Foods (Basel, Switzerland) · 2024Article
- Exploring the Chemical Profile, In Vitro Antioxidant and Anti-Inflammatory Activities ofMolecules (Basel, Switzerland) · 2024Article
- Polyphenols-Enrichment of Vienna Sausages Using Microcapsules Containing Acidic Aqueous Extract ofFoods (Basel, Switzerland) · 2024Article
- Antioxidant and Antibacterial Activities Evaluation, Phytochemical Characterisation of Rhizome fromTheScientificWorldJournal · 2024Article
- Emerging Insights into the Applicability of Essential Oils in the Management of Acne Vulgaris.Molecules (Basel, Switzerland) · 2023Review
- Determination of Coenzyme Q10 Content in Food By-Products and Waste by High-Performance Liquid Chromatography Coupled with Diode Array Detection.Foods (Basel, Switzerland) · 2023Article
- Materials Derived from Olive Pomace as Effective Bioadsorbents for the Process of Removing Total Phenols from Oil Mill Effluents.Molecules (Basel, Switzerland) · 2023Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Over the past decade, there has been growing interest in polyphenols' research since these compounds, as antioxidants, have several health benefits, such as preventing neurodegenerative diseases, inflammation, cancer, cardiovascular diseases, and type 2 diabetes. This study implements an analytical method to assess the total phenolic content (TPC) in essential oils using Folin-Ciocalteu's phenol reagent and quantifies the individual phenolic compounds by liquid chromatography. Thus, the research design and methodology included: (1) extraction of essential oil from dried thyme leaves by hydrodistillation; (2) spectrophotometric measurement of TPC by Folin-Ciocalteu method; and (3) identification and quantification of individual phenolic compounds by high-performance liquid chromatography-diode array detection/electrospray ionization mass spectrometry (HPLC-DAD-ESI-MS). Results revealed a TPC of 22.62 ± 0.482 mg GAE/100 µL and a polyphenolic profile characterized by phenolic acids (52.1%), flavonoids (16.1%), and other polyphenols (31.8%). Thymol, salvianolic acid A, and rosmarinic acid were the major compounds of thyme essential oil. The proposed analytical procedure has an acceptable level of repeatability, reproducibility, linearity, LOD (limit of detection), and LOQ (limit of quantification).
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