Evidence map›Paper›PMID 35209079›Full record

ArticleMolecules (Basel, Switzerland)2022

Induction of Liver Size Reduction in Zebrafish Larvae by the Emerging Synthetic Cannabinoid 4F-MDMB-BINACA and Its Impact on Drug Metabolism.

Yu Mi Park, Charlotte Dahlem, Markus R Meyer, Alexandra K Kiemer, Rolf Müller, Jennifer Herrmann

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.1field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

  1. Exploring Cannabinoid Effects Using Zebrafish (International journal of molecular sciences · 2025
    Review
  2. Article
  3. Review
  4. Zebrafish as an Animal Model in Cannabinoid Research.International journal of molecular sciences · 2023
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Yu Mi ParkHelmholtz Centre for Infection Research, Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Campus E8 1, Saarland University, 66123 Saarbrücken, Germany.
Charlotte DahlemDepartment of Pharmacy, Pharmaceutical Biology, Campus C2 3, Saarland University, 66123 Saarbrücken, Germany.ORCID 0000-0001-9983-0802
Markus R MeyerCenter for Molecular Signaling (PZMS), Institute of Experimental and Clinical Pharmacology and Toxicology, Department of Experimental and Clinical Toxicology, Saarland University, 66421 Homburg, Germany.
Alexandra K KiemerDepartment of Pharmacy, Pharmaceutical Biology, Campus C2 3, Saarland University, 66123 Saarbrücken, Germany.ORCID 0000-0002-7224-9900
Rolf MüllerHelmholtz Centre for Infection Research, Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Campus E8 1, Saarland University, 66123 Saarbrücken, Germany.
Jennifer HerrmannHelmholtz Centre for Infection Research, Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Campus E8 1, Saarland University, 66123 Saarbrücken, Germany.ORCID 0000-0003-3398-9938
Saarland University · DEGerman Center for Infection Research · DEKIST Europe · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Zebrafish (ZF;

Indexed as

AnimalsCannabinoidsChemical PhenomenaInactivation, MetabolicLarvaLiverMetabolic Networks and PathwaysMolecular StructureOrgan SizeReceptors, CannabinoidSpectrometry, Mass, Matrix-Assisted Laser Desorption-IonizationZebrafishCannabinoidsReceptors, Cannabinoidcannabinoid receptors (CB1 and CB2)drug metabolismhepatotoxicitymass spectrometry imaging (MSI)methyl 2-[1-(4-fluorobutyl)-1H-indazole-3-carboxamido]-3,3-dimethylbutanoate (4F-MDMB-BINACA)methyl 2-(1-(5-fluoropentyl)-1H-pyrrolo[2,3-b]pyridine-3-carboxamido)-3,3-dimethylbutanoate (7′N-5F-ADB)microinjectionmorpholino oligonucleotidessynthetic cannabinoid (SC)zebrafish larvae model

Identifiers

PMID35209079
PMCPMC8879502
OpenAlexW4213380860

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.