Evidence map›Paper›PMID 35208984›Full record

ReviewMolecules (Basel, Switzerland)2022

Some Natural Photosensitizers and Their Medicinal Properties for Use in Photodynamic Therapy.

Tomasz Piotr Kubrak, Przemysław Kołodziej, Jan Sawicki, Anna Mazur, Katarzyna Koziorowska, David Aebisher

Open access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed
15.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 106 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Targeted photodynamic therapy for MCF-7 breast cancer using antibody-conjugated, green-synthesized gold nanoparticles loaded with hypericin: a proof of concept.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2026
    Article
  6. Article
  7. Antimicrobial photodynamic therapy withFrontiers in cellular and infection microbiology · 2026
    Article
  8. Review
  9. Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Tomasz Piotr KubrakDepartment of Biochemistry and General Chemistry, The Medical College of The University of Rzeszów, 35-959 Rzeszów, Poland.ORCID 0000-0002-9905-7087
Przemysław KołodziejDepartment of Biology and Genetics, Medical University of Lublin, Chodzki 4a, 20-093 Lublin, Poland.ORCID 0000-0002-3710-0860
Jan SawickiDepartment of Analytical Chemistry, Medical University of Lublin, 20-093 Lublin, Poland.ORCID 0000-0002-5945-1047
Anna MazurBiochemistry Scientific Club "URCell", The Medical College of Rzeszów University, 35-959 Rzeszów, Poland.
Katarzyna KoziorowskaBiochemistry Science Club "English Division", The Medical College of Rzeszów University, 35-959 Rzeszów, Poland.
David AebisherDepartment of Photomedicine and Physical Chemistry, The Medical College of The University of Rzeszów, 35-959 Rzeszów, Poland.ORCID 0000-0002-2661-6570
University of Rzeszów · PLMedical University of Lublin · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite significant advances in early diagnosis and treatment, cancer is one of the leading causes of death. Photodynamic therapy (PDT) is a therapy for the treatment of many diseases, including cancer. This therapy uses a combination of a photosensitizer (PS), light irradiation of appropriate length and molecular oxygen. The photodynamic effect kills cancer cells through apoptosis, necrosis, or autophagy of tumor cells. PDT is a promising approach for eliminating various cancers but is not yet as widely applied in therapy as conventional chemotherapy. Currently, natural compounds with photosensitizing properties are being discovered and identified. A reduced toxicity to healthy tissues and a lower incidence of side effects inspires scientists to seek natural PS for PDT. In this review, several groups of compounds with photoactive properties are presented. The use of natural products has been shown to be a fruitful approach in the discovery of novel pharmaceuticals. This review focused on the anticancer activity of furanocoumarins, polyacetylenes, thiophenes, tolyporphins, curcumins, alkaloid and anthraquinones in relation to the light-absorbing properties. Attention will be paid to their phototoxic and anti-cancer effects on various types of cancer.

Indexed as

PhotochemotherapyBiological ProductsHumansNeoplasmsPhotosensitizing AgentsBiological ProductsPhotosensitizing Agentsalkaloidsanthraquinonescurcuminsfuranocoumarinsphotodynamic therapy (PDT)polyacetylenesthiophenestolyporphin

Identifiers

PMID35208984
PMCPMC8879555
OpenAlexW4211061211

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.