Evidence map›Paper›PMID 35208954›Full record

ArticleMolecules (Basel, Switzerland)2022

Halogenated Dihydropyrrol-2-One Molecules Inhibit Pyocyanin Biosynthesis by Blocking the

Theerthankar Das, Shekh Sabir, Ren Chen, Jessica Farrell, Frederik H Kriel, Gregory S Whiteley, Trevor O Glasbey, Jim Manos, Mark D P Willcox, Naresh Kumar

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 15 citations in OpenAlex.

  1. α-Mangostin attenuatesVirulence · 2026
    Article
  2. Review
  3. Review
  4. Quorum Sensing and its Inhibition inCurrent drug targets · 2025
    Review
  5. Article
  6. LC-MS/MS determination of pyocyanin-N-acetyl cysteine adduct: application for understanding Pseudomonas aeruginosa virulence factor neutralization.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2024
    Article
  7. Marine-Derived Furanones Targeting Quorum-Sensing Receptors inBioinformatics and biology insights · 2024
    Article
  8. Inhibition and eradication ofRSC medicinal chemistry · 2023
    Article
  9. Ascorbic acid modulates the structure of theFrontiers in microbiology · 2023
    Article
  10. The Molecular Architecture ofMarine drugs · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Theerthankar DasInfection, Immunity and Inflammation, Charles Perkins Centre, Sydney Institute for Infectious Diseases, School of Medical Sciences, The University of Sydney, Sydney, NSW 2006, Australia.
Shekh SabirSchool of Chemistry, The University of New South Wales, Sydney, NSW 2052, Australia.ORCID 0000-0002-3962-3040
Ren ChenSchool of Chemistry, The University of New South Wales, Sydney, NSW 2052, Australia.ORCID 0000-0003-0828-9980
Jessica FarrellInfection, Immunity and Inflammation, Charles Perkins Centre, Sydney Institute for Infectious Diseases, School of Medical Sciences, The University of Sydney, Sydney, NSW 2006, Australia.
Frederik H KrielWhiteley Corporation, 19-23 Laverick Avenue, Tomago, NSW 2322, Australia.
Gregory S WhiteleyWhiteley Corporation, 19-23 Laverick Avenue, Tomago, NSW 2322, Australia.ORCID 0000-0001-7830-1725
Trevor O GlasbeyWhiteley Corporation, 19-23 Laverick Avenue, Tomago, NSW 2322, Australia.
Jim ManosInfection, Immunity and Inflammation, Charles Perkins Centre, Sydney Institute for Infectious Diseases, School of Medical Sciences, The University of Sydney, Sydney, NSW 2006, Australia.ORCID 0000-0002-5765-1563
Mark D P WillcoxSchool of Optometry and Vision Science, The University of New South Wales, Sydney, NSW 2052, Australia.ORCID 0000-0003-3842-7563
Naresh KumarSchool of Chemistry, The University of New South Wales, Sydney, NSW 2052, Australia.ORCID 0000-0002-0951-9621
UNSW Sydney · AUThe University of Sydney · AU

Funding

Australian Research Council grant DP180100845.Department of Industry, Science, Energy and Resources IMCRC/WLY/08052019.1.
6 · The paper itself

Abstract

Quorum-sensing (QS) systems of

Indexed as

Gene Expression Regulation, BacterialPseudomonas aeruginosaPyocyanineQuinolonesQuorum SensingPyocyanineQuinolonesdihydropyrrol-2-oneLasRP. aeruginosaPQSpyocyaninquorum sensing

Identifiers

PMID35208954
PMCPMC8875348
OpenAlexW4211136731

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.