Evidence map›Paper›PMID 35208871›Full record

ReviewMicroorganisms2022

Recent Antimicrobial Responses of Halophilic Microbes in Clinical Pathogens.

Henciya Santhaseelan, Vengateshwaran Thasu Dinakaran, Hans-Uwe Dahms, Johnthini Munir Ahamed, Santhosh Gokul Murugaiah, Muthukumar Krishnan, Jiang-Shiou Hwang, Arthur James Rathinam

Abstract readReview
In one paragraph

Review in Microorganisms, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Review
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  10. Review
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  14. Article
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  16. Article
  17. Metabolic Potential of Halophilic Filamentous Fungi-Current Perspective.International journal of molecular sciences · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Henciya SanthaseelanDepartment of Marine Science, Bharathidasan University, Tiruchirappalli 620024, India.
Vengateshwaran Thasu DinakaranDepartment of Marine Science, Bharathidasan University, Tiruchirappalli 620024, India.ORCID 0000-0001-5142-2412
Hans-Uwe DahmsDepartment of Biomedical Science and Environmental Biology, Kaohsiung Medical University, Kaohsiung 807, Taiwan.ORCID 0000-0002-0352-2715
Johnthini Munir AhamedDepartment of Biomedical Science and Environmental Biology, Kaohsiung Medical University, Kaohsiung 807, Taiwan.ORCID 0000-0003-0749-2864
Santhosh Gokul MurugaiahDepartment of Marine Science, Bharathidasan University, Tiruchirappalli 620024, India.
Muthukumar KrishnanDepartment of Physics, National Institute of Technology, Tiruchirappalli 620015, India.
Jiang-Shiou HwangInstitute of Marine Biology, National Taiwan Ocean University, Keelung 20224, Taiwan.ORCID 0000-0003-4881-1163
Arthur James RathinamDepartment of Marine Science, Bharathidasan University, Tiruchirappalli 620024, India.ORCID 0000-0003-4536-4863

Funding

Center of Excellence for Ocean Engineering, NTOU, Taiwan Grant No. 109J13801-51, 110J13801-51Ministry of Science and Technology, Taiwan MOST 107-2621-M-019-001, MOST 108-2621-M-019-003, MOST 109-2621-M-019-002 and MOST 110-2621-M-019-001
6 · The paper itself

Abstract

Microbial pathogens that cause severe infections and are resistant to drugs are simultaneously becoming more active. This urgently calls for novel effective antibiotics. Organisms from extreme environments are known to synthesize novel bioprospecting molecules for biomedical applications due to their peculiar characteristics of growth and physiological conditions. Antimicrobial developments from hypersaline environments, such as lagoons, estuaries, and salterns, accommodate several halophilic microbes. Salinity is a distinctive environmental factor that continuously promotes the metabolic adaptation and flexibility of halophilic microbes for their survival at minimum nutritional requirements. A genetic adaptation to extreme solar radiation, ionic strength, and desiccation makes them promising candidates for drug discovery. More microbiota identified via sequencing and 'omics' approaches signify the hypersaline environments where compounds are produced. Microbial genera such as

Indexed as

antibiotic resistancebioactive compoundhalophilicpharmaceuticalsalinity

Identifiers

PMID35208871
PMCPMC8874722

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.