Evidence map›Paper›PMID 35208853›Full record

ArticleMicroorganisms2022

Simvastatin Resistance of

Thais Tenorio Soares Fujii, Pollyanna Stephanie Gomes, Rubens Lima do Monte-Neto, Daniel Claudio de Oliveira Gomes, Marc Ouellette, Eduardo Caio Torres-Santos, Valter Viana Andrade-Neto, Herbert Leonel de Matos Guedes

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Microorganisms, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. The therapeutic potential of atorvastatin in treatment ofFrontiers in veterinary science · 2026
    Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Thais Tenorio Soares FujiiLaboratório de Imunofarmacologia, Instituto de Biofísica Carlos Chagas Filho (IBCCF), Universidade Federal do Rio de Janeiro, Rio de Janeiro 21941-901, Brazil.
Pollyanna Stephanie GomesLaboratório de Imunobiotecnologia, Instituto de Microbiologia Paulo de Góes, Universidade Federal do Rio de Janeiro, Rio de Janeiro 21941-901, Brazil.
Rubens Lima do Monte-NetoGrupo de Pesquisas em Biotecnologia Aplicada a Patógenos-Instituto René Rachou, Fundação Oswaldo Cruz-Fiocruz Minas, Belo Horizonte 30190-002, Brazil.ORCID 0000-0002-4688-2462
Daniel Claudio de Oliveira GomesNúcleo de Doenças Infecciosas, Universidade Federal do Espírito Santo, Vitória 29075-910, Brazil.
Marc OuelletteCHU de Quebec Research Center, Division of Infectious Disease and Immunity, Department of Microbiology Infectious Disease and Immunology, Laval University, Quebec, QC G1V 4G2, Canada.
Eduardo Caio Torres-SantosLaboratório de Bioquímica de Tripanosomatídeos, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz-Fiocruz, Rio de Janeiro 21040-900, Brazil.ORCID 0000-0003-2240-4519
Valter Viana Andrade-NetoLaboratório de Bioquímica de Tripanosomatídeos, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz-Fiocruz, Rio de Janeiro 21040-900, Brazil.ORCID 0000-0001-8854-1896
Herbert Leonel de Matos GuedesLaboratório de Imunofarmacologia, Instituto de Biofísica Carlos Chagas Filho (IBCCF), Universidade Federal do Rio de Janeiro, Rio de Janeiro 21941-901, Brazil.
Fundação Oswaldo Cruz · BRUniversidade Federal do Rio de Janeiro · BRUniversidade Federal do Espírito Santo · BRUniversité Laval · CA

Funding

National Council for Scientific and Technological Development 310640/2017-2
6 · The paper itself

Abstract

The sterol biosynthesis pathway of

Indexed as

HMG-CoA reductaseLeishmania amazonensispharmacological targetserine proteasessimvastatin resistancesterol pathway

Identifiers

PMID35208853
PMCPMC8877030
OpenAlexW4210995635

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.