ArticleMicroorganisms2022
Investigating Morphological Changes of T-lymphocytes after Exposure with Bacterial Determinants for Early Detection of Septic Conditions.
Article in Microorganisms, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
5 citing papers in PubMed.
- Article
- Three-dimensional label-free morphology of CD8 + T cells as a sepsis biomarker.Light, science & applications · 2023Article
- Article
- Virulence Factors and Antibiotic Resistance of Enterobacterales.Microorganisms · 2022Article
- Chemotherapy drug potency assessment method of ovarian cancer cells by digital holography microscopy.Biomedical optics express · 2022Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
Sepsis is a leading cause of morbidity and mortality, annually affecting millions of people worldwide. Immediate treatment initiation is crucial to improve the outcome but despite great progress, early identification of septic patients remains a challenge. Recently, white blood cell morphology was proposed as a new biomarker for sepsis diagnosis. In this proof-of-concept study, we aimed to investigate the effect of different bacteria and their determinants on T-lymphocytes by digital holographic microscopy (DHM). We hypothesize that species- and strain-specific morphological changes occur, which may offer a new approach for early sepsis diagnosis and identification of the causative agent. Jurkat cells as a model system were exposed to different
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