Evidence map›Paper›PMID 35208762›Full record

ReviewMicroorganisms2022

Algae and Their Metabolites as Potential Bio-Pesticides.

Elias Asimakis, Awad A Shehata, Wolfgang Eisenreich, Fatma Acheuk, Salma Lasram, Shereen Basiouni, Mevlüt Emekci, Spyridon Ntougias, Gökçe Taner, Helen May-Simera and 2 more

Open access · goldAbstract readReview
In one paragraph

Review in Microorganisms, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
4.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 95 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Review
  10. CyanobacteriumFrontiers in microbiology · 2025
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Fungus-based bioherbicides on circular economy.Bioprocess and biosystems engineering · 2023
    Review
  16. Review
  17. Article
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 8 institutions in 5 countries.

Elias AsimakisLaboratory of Systems Microbiology and Applied Genomics, Department of Environmental Engineering, University of Patras, 2 Seferi St., 30131 Agrinio, Greece.ORCID 0000-0001-9109-1750
Awad A ShehataResearch and Development Section, PerNaturam GmbH, 56290 Gödenroth, Germany.
Wolfgang EisenreichBavarian NMR Center-Structural Membrane Biochemistry, Department of Chemistry, Technische Universität München, 85748 Garching, Germany.ORCID 0000-0002-9832-8279
Fatma AcheukLaboratory for Valorization and Conservation of Biological Resources, Faculty of Sciences, University M'Hamed Bougara of Boumerdes, Boumerdes 35000, Algeria.
Salma LasramLaboratory of Molecular Physiology of Plants, Borj-Cedria Biotechnology Center. BP. 901, Hammam-Lif 2050, Tunisia.
Shereen BasiouniInstitute of Molecular Physiology, Johannes Gutenberg-University of Mainz, 55128 Mainz, Germany.
Mevlüt EmekciDepartment of Plant Protection, Faculty of Agriculture, Ankara University, Keçiören, Ankara 06135, Turkey.
Spyridon NtougiasDepartment of Environmental Engineering, Democritus University of Thrace, Vas. Sofias 12, 67132 Xanthi, Greece.ORCID 0000-0002-6389-692X
Gökçe TanerDepartment of Bioengineering, Bursa Technical University, Bursa 16310, Turkey.ORCID 0000-0002-0290-1166
Helen May-SimeraInstitute of Molecular Physiology, Johannes Gutenberg-University of Mainz, 55128 Mainz, Germany.ORCID 0000-0002-9477-4036
Mete YilmazDepartment of Bioengineering, Bursa Technical University, Bursa 16310, Turkey.
George TsiamisLaboratory of Systems Microbiology and Applied Genomics, Department of Environmental Engineering, University of Patras, 2 Seferi St., 30131 Agrinio, Greece.ORCID 0000-0001-5616-8505
Bursa Technical University · TRJohannes Gutenberg University Mainz · DEUniversity of Patras · GRAnkara University · TRCenter of Biotechnogy of Borj Cédria · TNDemocritus University of Thrace · GRTechnical University of Munich · DEUniversity of Boumerdes · DZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An increasing human population necessitates more food production, yet current techniques in agriculture, such as chemical pesticide use, have negative impacts on the ecosystems and strong public opposition. Alternatives to synthetic pesticides should be safe for humans, the environment, and be sustainable. Extremely diverse ecological niches and millions of years of competition have shaped the genomes of algae to produce a myriad of substances that may serve humans in various biotechnological areas. Among the thousands of described algal species, only a small number have been investigated for valuable metabolites, yet these revealed the potential of algal metabolites as bio-pesticides. This review focuses on macroalgae and microalgae (including cyanobacteria) and their extracts or purified compounds, that have proven to be effective antibacterial, antiviral, antifungal, nematocides, insecticides, herbicides, and plant growth stimulants. Moreover, the mechanisms of action of the majority of these metabolites against plant pests are thoroughly discussed. The available information demonstrated herbicidal activities via inhibition of photosynthesis, antimicrobial activities via induction of plant defense responses, inhibition of quorum sensing and blocking virus entry, and insecticidal activities via neurotoxicity. The discovery of antimetabolites also seems to hold great potential as one recent example showed antimicrobial and herbicidal properties. Algae, especially microalgae, represent a vast untapped resource for discovering novel and safe biopesticide compounds.

Indexed as

algal extractsantimicrobialcyanobacteriaphotosynthesisplant defense

Identifiers

PMID35208762
PMCPMC8877611
OpenAlexW4210730772

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.