Evidence map›Paper›PMID 35208761›Full record

ArticleMicroorganisms2022

Comparative Analysis of Five Multiplex RT-PCR Assays in the Screening of SARS-CoV-2 Variants.

Vanessa De Pace, Bianca Bruzzone, Andrea Orsi, Valentina Ricucci, Alexander Domnich, Giulia Guarona, Nadia Randazzo, Federica Stefanelli, Enrico Battolla, Pier Andrea Dusi and 2 more

Abstract read
In one paragraph

Article in Microorganisms, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Review
  2. Observational
  3. Article
  4. Article
  5. Observational
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Rapid and qualitative identification of SARS-CoV-2 mutations associated with variants of concern using a multiplex RT-PCR assay coupled with melting analysis.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2022
    Article
  15. Review
  16. A robust, highly multiplexed mass spectrometry assay to identify SARS-CoV-2 variants.medRxiv : the preprint server for health sciences · 2022
    Article
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Vanessa De PaceHygiene Unit, Ospedale Policlinico San Martino-IRCCS, 16132 Genoa, Italy.ORCID 0000-0002-9822-6520
Bianca BruzzoneHygiene Unit, Ospedale Policlinico San Martino-IRCCS, 16132 Genoa, Italy.
Andrea OrsiDepartment of Health Sciences (DISSAL), University of Genoa, 16132 Genoa, Italy.ORCID 0000-0002-2433-9610
Valentina RicucciHygiene Unit, Ospedale Policlinico San Martino-IRCCS, 16132 Genoa, Italy.
Alexander DomnichHygiene Unit, Ospedale Policlinico San Martino-IRCCS, 16132 Genoa, Italy.ORCID 0000-0001-9608-8892
Giulia GuaronaDepartment of Health Sciences (DISSAL), University of Genoa, 16132 Genoa, Italy.ORCID 0000-0002-4274-0096
Nadia RandazzoHygiene Unit, Ospedale Policlinico San Martino-IRCCS, 16132 Genoa, Italy.
Federica StefanelliHygiene Unit, Ospedale Policlinico San Martino-IRCCS, 16132 Genoa, Italy.
Enrico BattollaDivision of Clinical Pathology, Azienda Sanitaria Locale n°5, 19121 La Spezia, Italy.
Pier Andrea DusiMicrobiology Department, Sanremo Hospital, 18038 Imperia, Italy.
Flavia LilloLaboratory of Clinical Pathology, ASL2 Savonese, 17100 Savona, Italy.ORCID 0000-0001-8132-1823
Giancarlo IcardiDepartment of Health Sciences (DISSAL), University of Genoa, 16132 Genoa, Italy.ORCID 0000-0002-8463-8487

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The rapid and presumptive detection of SARS-CoV-2 variants may be performed using multiplex RT-PCR assays. The aim of this study was to evaluate the diagnostic performance of five qualitative RT-PCR tests as compared with next-generation sequencing (NGS). We retrospectively examined a multi-variant panel (

Indexed as

diagnosticspandemicsurveillance

Identifiers

PMID35208761
PMCPMC8876857

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.