Evidence map›Paper›PMID 35208724›Full record

ArticleMicroorganisms2022

First Case of a COVID-19 Patient Infected by Delta AY.4 with a Rare Deletion Leading to a N Gene Target Failure by a Specific Real Time PCR Assay: Novel Omicron VOC Might Be Doing Similar Scenario?

Mohammad Alkhatib, Maria Concetta Bellocchi, Greta Marchegiani, Sandro Grelli, Valeria Micheli, Daniele Stella, Bartolomeo Zerillo, Luca Carioti, Valentina Svicher, Paola Rogliani and 1 more

Open access · goldAbstract readCase Reports
In one paragraph

Article in Microorganisms, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Mohammad AlkhatibDepartment of Experimental Medicine, University of Rome Tor Vergata, 00133 Rome, Italy.ORCID 0000-0003-0085-8990
Maria Concetta BellocchiDepartment of Experimental Medicine, University of Rome Tor Vergata, 00133 Rome, Italy.
Greta MarchegianiDepartment of Experimental Medicine, University of Rome Tor Vergata, 00133 Rome, Italy.
Sandro GrelliDepartment of Experimental Medicine, University of Rome Tor Vergata, 00133 Rome, Italy.
Valeria MicheliLaboratory of Clinical Microbiology, Virology and Bioemergencies, ASST Fatebenefratelli Sacco L. Sacco Hospital, 20157 Milan, Italy.ORCID 0000-0001-5629-3875
Daniele StellaDepartment of Experimental Medicine, University of Rome Tor Vergata, 00133 Rome, Italy.
Bartolomeo ZerilloRespiratory Medicine Unit, Policlinico Tor Vergata, 00133 Rome, Italy.
Luca CariotiDepartment of Experimental Medicine, University of Rome Tor Vergata, 00133 Rome, Italy.
Valentina SvicherDepartment of Biology, University of Rome Tor Vergata, 00133 Rome, Italy.
Paola RoglianiDepartment of Experimental Medicine, University of Rome Tor Vergata, 00133 Rome, Italy.ORCID 0000-0001-7801-5040
Francesca Ceccherini-SilbersteinDepartment of Experimental Medicine, University of Rome Tor Vergata, 00133 Rome, Italy.
University of Rome Tor Vergata · ITASST Fatebenefratelli Sacco · ITPoliclinico Tor Vergata · IT

Funding

EuCARE project "European cohorts of patients and schools to advance response to epidemics" funded by the EC under HORIZON-HLTH-2021-CORONA-01 101046016Italian Ministry of Research FISR2020IP_04758
6 · The paper itself

Abstract

Herein, we report a case of an Italian male infected by Delta sublineage AY.4 harboring an atypical deletion, leading to a N gene target failure (NGTF) by a commercial molecular assay for SARS-CoV-2 diagnosis (Allplex

Indexed as

delta variantdiagnostic assayN gene target failureNGSnucleocapsid deletionomicron variantSARS-CoV-2sequence

Identifiers

PMID35208724
PMCPMC8875198
OpenAlexW4210428626

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.