Evidence map›Paper›PMID 35208450›Full record

ReviewMicromachines2022

The Biofabrication of Diseased Artery In Vitro Models.

Chen Pan, Qiqi Gao, Byoung-Soo Kim, Yafeng Han, Ge Gao

Abstract readReview
In one paragraph

Review in Micromachines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Chen PanInstitute of Engineering Medicine, Beijing Institute of Technology, Beijing 100081, China.ORCID 0000-0002-1793-7217
Qiqi GaoInstitute of Engineering Medicine, Beijing Institute of Technology, Beijing 100081, China.
Byoung-Soo KimSchool of Biomedical Convergence Engineering, Pusan National University, Yangsan 626841, Korea.ORCID 0000-0002-6693-0003
Yafeng HanSchool of Mechanical Engineering, Beijing Institute of Technology, Beijing 100081, China.
Ge GaoInstitute of Engineering Medicine, Beijing Institute of Technology, Beijing 100081, China.ORCID 0000-0003-3328-2879

Funding

Beijing Institute of Technology Research Fund Program for Young Scholars XSQD-202123003
6 · The paper itself

Abstract

As the leading causes of global death, cardiovascular diseases are generally initiated by artery-related disorders such as atherosclerosis, thrombosis, and aneurysm. Although clinical treatments have been developed to rescue patients suffering from artery-related disorders, the underlying pathologies of these arterial abnormalities are not fully understood. Biofabrication techniques pave the way to constructing diseased artery in vitro models using human vascular cells, biomaterials, and biomolecules, which are capable of recapitulating arterial pathophysiology with superior performance compared with conventional planar cell culture and experimental animal models. This review discusses the critical elements in the arterial microenvironment which are important considerations for recreating biomimetic human arteries with the desired disorders in vitro. Afterward, conventionally biofabricated platforms for the investigation of arterial diseases are summarized, along with their merits and shortcomings, followed by a comprehensive review of advanced biofabrication techniques and the progress of their applications in establishing diseased artery models.

Indexed as

arterial diseasesbiofabrication techniquesin vitro modelstissue microenvironment

Identifiers

PMID35208450
PMCPMC8874977

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.