Evidence map›Paper›PMID 35208428›Full record

ArticleMicromachines2022

Electrochemical Sensing of Glucose Using Glucose Oxidase/PEDOT:4-Sulfocalix [4]arene/MXene Composite Modified Electrode.

Preethika Murugan, Jayshree Annamalai, Raji Atchudan, Mani Govindasamy, Deepak Nallaswamy, Dhanraj Ganapathy, Anatoly Reshetilov, Ashok K Sundramoorthy

Abstract read
In one paragraph

Article in Micromachines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

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  19. MnBiosensors · 2023
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Preethika MuruganDepartment of Chemistry, SRM Institute of Science and Technology, Kattankulathur 603203, Tamil Nadu, India.
Jayshree AnnamalaiDepartment of Biotechnology, SRM Institute of Science and Technology, Kattankulathur 603203, Tamil Nadu, India.
Raji AtchudanSchool of Chemical Engineering, Yeungnam University, Gyeongsan 38541, Korea.ORCID 0000-0001-8793-0953
Mani GovindasamyDepartment of Materials Engineering, Ming-Chi University of Technology, New Taipei City 243, Taiwan.ORCID 0000-0001-6701-6507
Deepak NallaswamyDepartment of Prosthodontics, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Poonamallee High Road, Velappanchavadi, Chennai 600077, Tamil Nadu, India.
Dhanraj GanapathyDepartment of Prosthodontics, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Poonamallee High Road, Velappanchavadi, Chennai 600077, Tamil Nadu, India.
Anatoly ReshetilovG.K. Skryabin Institute of Biochemistry and Physiology of Microorganisms, Pushchino Centre for Biological Research, Russian Academy of Sciences, 142290 Pushchino, Russia.ORCID 0000-0002-9607-253X
Ashok K SundramoorthyDepartment of Chemistry, SRM Institute of Science and Technology, Kattankulathur 603203, Tamil Nadu, India.ORCID 0000-0002-8512-9393

Funding

Department of Science and Technology INT/RUS/RFBR/385
6 · The paper itself

Abstract

Glucose is one of the most important monosaccharides found in the food, as a part of more complex structures, which is a primary energy source for the brain and body. Thus, the monitoring of glucose concentration is more important in food and biological samples in order to maintain a healthy lifestyle. Herein, an electrochemical glucose biosensor was fabricated by immobilization of glucose oxidase (GOX) onto poly(3,4-ethylenedioxythiophene):4-sulfocalix [4]arene (PEDOT:SCX)/MXene modified electrode. For this purpose, firstly, PEDOT was synthesized in the presence of SCX (counterion) by the chemical oxidative method. Secondly, MXene (a 2D layered material) was synthesized by using a high-temperature furnace under a nitrogen atmosphere. After that, PEDOT:SCX/MXene (1:1) dispersion was prepared by ultrasonication which was later utilized to prepare PEDOT:SCX/MXene hybrid film. A successful formation of PEDOT:SCX/MXene film was confirmed by HR-SEM, Fourier transform infrared (FT-IR), and Raman spectroscopies. Due to the biocompatibility nature, successful immobilization of GOX was carried out onto chitosan modified PEDOT:SCX/MXene/GCE. Moreover, the electrochemical properties of PEDOT:SCX/MXene/GOX/GCE was studied through cyclic voltammetry and amperometry methods. Interestingly, a stable redox peak of FAD-GOX was observed at a formal potential of -0.435 V on PEDOT:SCX/MXene/GOX/GCE which indicated a direct electron transfer between the enzyme and the electrode surface. PEDOT:SCX/MXene/GOX/GCE also exhibited a linear response against glucose concentrations in the linear range from 0.5 to 8 mM. The effect of pH, sensors reproducibility, and repeatability of the PEDOT:SCX/MXene/GOX/GCE sensor were studied. Finally, this new biosensor was successfully applied to detect glucose in commercial fruit juice sample with satisfactory recovery.

Indexed as

4-sulfocalix [4]areneelectrochemical sensorglucose oxidaseMXenePEDOT

Identifiers

PMID35208428
PMCPMC8877456

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.