Evidence map›Paper›PMID 35208349›Full record

ArticleMicromachines2022

Angiogenesis and Functional Vessel Formation Induced by Interstitial Flow and Vascular Endothelial Growth Factor Using a Microfluidic Chip.

Yufang Liu, Jiao Li, Jiasheng Zhou, Xue Liu, Huibing Li, Yao Lu, Bingcheng Lin, Xiaojie Li, Tingjiao Liu

Abstract read
In one paragraph

Article in Micromachines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Bioengineering vascularization.Development (Cambridge, England) · 2024
    Review
  7. Review
  8. Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Advances in the Model Structure of In Vitro Vascularized Organ-on-a-Chip.Cyborg and bionic systems (Washington, D.C.) · 2024
    Article
  15. Review
  16. Review
  17. Exploring Endothelial Expansion on a Chip.Sensors (Basel, Switzerland) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yufang LiuDepartment of Oral Pathology, Shanghai Stomatological Hospital & School of Stomatology, Fudan University, Tianjin Road No. 2, Huangpu District, Shanghai 200001, China.
Jiao LiDepartment of Oral Pathology, Shanghai Stomatological Hospital & School of Stomatology, Fudan University, Tianjin Road No. 2, Huangpu District, Shanghai 200001, China.
Jiasheng ZhouSchool of Stomatology, Dalian Medical University, West Section No. 9, Sourth Road of Lvshun, Dalian 116044, China.
Xue LiuDepartment of Oral Pathology, Shanghai Stomatological Hospital & School of Stomatology, Fudan University, Tianjin Road No. 2, Huangpu District, Shanghai 200001, China.
Huibing LiSchool of Stomatology, Dalian Medical University, West Section No. 9, Sourth Road of Lvshun, Dalian 116044, China.
Yao LuDepartment of Biotechnology, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Zhongshan Road No. 456, Dalian 116023, China.ORCID 0000-0002-2169-6479
Bingcheng LinDepartment of Biotechnology, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Zhongshan Road No. 456, Dalian 116023, China.
Xiaojie LiSchool of Stomatology, Dalian Medical University, West Section No. 9, Sourth Road of Lvshun, Dalian 116044, China.
Tingjiao LiuDepartment of Oral Pathology, Shanghai Stomatological Hospital & School of Stomatology, Fudan University, Tianjin Road No. 2, Huangpu District, Shanghai 200001, China.ORCID 0000-0002-3115-7620

Funding

Tingjiao Liu 82073001;2020JJ26SN053;SSDC-2021-RC01
6 · The paper itself

Abstract

Angiogenesis occurs during both physiological and pathological processes. In this study, a microfluidic chip for the development of angiogenesis was utilized to assess angiogenic sprouting and functional vessel formation. We also found that vascular endothelial growth factor (VEGF) was a determinant of the initiation of vascular sprouts, while the direction of these sprouts was greatly influenced by interstitial flow. Isoforms of VEGF such as VEGF

Indexed as

angiogenesisinterstitial flowmicrofluidicVEGF

Identifiers

PMID35208349
PMCPMC8876009

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.