Evidence map›Paper›PMID 35208324›Full record

ReviewMicromachines2022

Microfluidic Applications in Drug Development: Fabrication of Drug Carriers and Drug Toxicity Screening.

Pei Zhao, Jianchun Wang, Chengmin Chen, Jianmei Wang, Guangxia Liu, Krishnaswamy Nandakumar, Yan Li, Liqiu Wang

Abstract readReview
In one paragraph

Review in Micromachines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Microfluidic Formulation for Biomedical Applications.Pharmaceuticals (Basel, Switzerland) · 2023
    Article
  4. Droplet-Based Microfluidics: Applications in Pharmaceuticals.Pharmaceuticals (Basel, Switzerland) · 2023
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Pei ZhaoEnergy Institute, Qilu University of Technology (Shandong Academy of Sciences), Jinan 250014, China.
Jianchun WangEnergy Institute, Qilu University of Technology (Shandong Academy of Sciences), Jinan 250014, China.
Chengmin ChenEnergy Institute, Qilu University of Technology (Shandong Academy of Sciences), Jinan 250014, China.
Jianmei WangEnergy Institute, Qilu University of Technology (Shandong Academy of Sciences), Jinan 250014, China.ORCID 0000-0003-1694-6848
Guangxia LiuEnergy Institute, Qilu University of Technology (Shandong Academy of Sciences), Jinan 250014, China.
Krishnaswamy NandakumarEnergy Institute, Qilu University of Technology (Shandong Academy of Sciences), Jinan 250014, China.
Yan LiEnergy Institute, Qilu University of Technology (Shandong Academy of Sciences), Jinan 250014, China.ORCID 0000-0002-8044-3746
Liqiu WangDepartment of Mechanical Engineering, Faculty of Engineering, The University of Hong Kong, Hong Kong 999077, China.ORCID 0000-0002-6514-4211

Funding

Integration Project of Science, Education and Industry in Qilu University of Technology (Shandong Academy of Sciences) 2020KJC-YJ04 and -YJ03Provincial key R&D project 2021CXGC010515the Double Hundred Plan of Shandong Province WST2017001the international S&T cooperation program of Shandong Academy of Sciences 2019GHPY06the Pilot Project Scheme of Shandong Academy of Sciences 2013-2018
6 · The paper itself

Abstract

Microfluidic technology has been highly useful in nanovolume sample preparation, separation, synthesis, purification, detection and assay, which are advantageous in drug development. This review highlights the recent developments and trends in microfluidic applications in two areas of drug development. First, we focus on how microfluidics has been developed as a facile tool for the fabrication of drug carriers including microparticles and nanoparticles. Second, we discuss how microfluidic chips could be used as an independent platform or integrated with other technologies in drug toxicity screening. Challenges and future perspectives of microfluidic applications in drug development have also been provided considering the present technological limitations.

Indexed as

drug carrierdrug developmentdrug toxicity screeningmicrofluidic technologymicro/nanoparticlesorgans-on-chips

Identifiers

PMID35208324
PMCPMC8877367

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.