ArticleMetabolites2022
The Endogenous Metabolite Glycerophosphocholine Promotes Longevity and Fitness in
Article in Metabolites, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed, 23 citations in OpenAlex.
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- Metabolomic and proteomic differences in susceptible and benzimidazole-resistant adult females and males of Haemonchus contortus.Veterinary research · 2025Article
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- A Hydrolyzed Soybean Protein Enhances Oxidative Stress Resistance inAntioxidants (Basel, Switzerland) · 2025Article
- Non-Mammalian Models for Understanding Neurological Defects in RASopathies.Biomedicines · 2024Review
- Effects ofFrontiers in microbiology · 2024Article
- Anti-aging effect of glycerophosphocholine inFrontiers in physiology · 2024Article
- Dauer larva-derived extracellular vesicles extend the life of Caenorhabditis elegans.Biogerontology · 2023Article
- Polygonati Rhizoma Polysaccharide Prolongs Lifespan and Healthspan inMolecules (Basel, Switzerland) · 2023Article
- Metabolite Changes in Orange Dead Leaf ButterflyMetabolites · 2022Article
Corrections and comments
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Authors and funding
12 authors at 1 institution in 1 country.
Funding
Abstract
Metabolism and aging are closely connected. The choline derivative glycerophosphocholine (GPC), an important precursor of the neurotransmitter acetylcholine, plays important roles in brain and nervous system function. Although it has been reported to alleviate cognitive decline in aged mice, whether GPC could promote longevity and other fitness factors remains unclear. Here, we find endogenous GPC level declines in the plasma of ageing humans. In
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.