Evidence map›Paper›PMID 35208182›Full record

ArticleMetabolites2022

Bioinformatics Modelling and Metabolic Engineering of the Branched Chain Amino Acid Pathway for Specific Production of Mycosubtilin Isoforms in

Jean-Sébastien Guez, Françoise Coucheney, Joany Guy, Max Béchet, Pierre Fontanille, Nour-Eddine Chihib, Joachim Niehren, François Coutte, Philippe Jacques

Open access · goldAbstract read
In one paragraph

Article in Metabolites, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 8 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 5 countries.

Jean-Sébastien GuezInstitut Pascal, Clermont Auvergne INP, CNRS, Université Clermont Auvergne, F-63000 Clermont-Ferrand, France.ORCID 0000-0002-8736-7758
Françoise CoucheneyÉquipe Métabolites Secondaires d'Origine Microbienne, Institut Charles Viollette, UMRt BioEcoAgro 1158-INRAE, Université de Lille, F-59000 Lille, France.ORCID 0000-0001-8599-5841
Joany GuyÉquipe Métabolites Secondaires d'Origine Microbienne, Institut Charles Viollette, UMRt BioEcoAgro 1158-INRAE, Université de Lille, F-59000 Lille, France.
Max BéchetÉquipe Métabolites Secondaires d'Origine Microbienne, Institut Charles Viollette, UMRt BioEcoAgro 1158-INRAE, Université de Lille, F-59000 Lille, France.
Pierre FontanilleInstitut Pascal, Clermont Auvergne INP, CNRS, Université Clermont Auvergne, F-63000 Clermont-Ferrand, France.ORCID 0000-0003-1066-7039
Nour-Eddine ChihibUMR 8207-UMET-Unité Matériaux et Transformations, Centrale Lille, INRAE, CNRS, Université de Lille, F-59000 Lille, France.
Joachim NiehrenBiocomputing Team, Centre de Recherche en Informatique, Signal et Automatique de Lille CRIStAL, UMR CNRS 9189, Université de Lille, F-59000 Lille, France.ORCID 0000-0002-2611-8950
François CoutteÉquipe Métabolites Secondaires d'Origine Microbienne, Institut Charles Viollette, UMRt BioEcoAgro 1158-INRAE, Université de Lille, F-59000 Lille, France.ORCID 0000-0002-5233-1181
Philippe JacquesÉquipe Métabolites Spécialisés d'Origine Microbienne, UMRt BioEcoAgro 1158-INRAE, TERRA Teaching and Research Centre, MiPI, Gembloux Agro-Bio Tech, Université de Liège, B-5030 Gembloux, Belgium.
Centre National de la Recherche Scientifique · FRUniversité de Lille · FRUniversity of Liège · BE

Funding

haut de france region ALIBIOTECH
6 · The paper itself

Abstract

Mycosubtilin belongs to the family of lipopeptides. Different isoforms with various antifungal activities can be obtained according to the length and the isomery of the fatty acid. In this work, the activities of the mycosubtilin isoforms were first studied against the pathogen

Indexed as

antifungalBacillus subtilisbioinformatic modellingbranched chain amino acidsfatty acidslipopeptidesmetabolic engineeringmycosubtilin

Identifiers

PMID35208182
PMCPMC8877110
OpenAlexW4210817322

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.