ArticleMaterials (Basel, Switzerland)2022
Dentin Biomodification with Flavonoids and Calcium Phosphate Ion Clusters to Improve Dentin Bonding Stability.
Article in Materials (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
7 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Biomimetic Remineralization Strategies for Dentin Bond Stability-Systematic Review and Network Meta-Analysis.International journal of molecular sciences · 2025Pooled it
- Effect of collagen cross-linkers on dentin bond strength: A systematic review and network meta-analysis.Frontiers in bioengineering and biotechnology · 2022Pooled it
- Nature's Cross-linkers:International journal of clinical pediatric dentistry · 2026Article
- Pomegranate extract on eroded dentin: antioxidant action, bond strength and morphology of the adhesive interface after aging.Restorative dentistry & endodontics · 2024Article
- The effect of kaempferol on the dentin bonding stability through matrix metalloproteinases inhibition and collagen crosslink in dentin biomodification.Journal of dental sciences · 2023Article
- Analyses of Experimental Dental Adhesives Based on Zirconia/Silver Phosphate Nanoparticles.Polymers · 2023Article
- The Effect of Biomimetic Remineralization of Calcium Phosphate Ion Clusters-Treated Enamel Surfaces on Bracket Shear Bond Strength.International journal of nanomedicine · 2023Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
The purpose of this study was to evaluate the effects of flavonoids and calcium phosphate ion clusters (CPIC) on dentin bonding stability. Seven experimental solutions were synthesized using icaritin (ICT), fisetin (FIS), silibinin (SIB), CPIC, and combinations of one of three flavonoids and CPIC (ICT + C, FIS + C, SIB + C). The experimental solutions were applied to demineralized dentin prior to the application of a universal adhesive. A group without any experimental solution served as a control. Dentin specimens pretreated with the experimental solutions were assayed using Fourier transform infrared (FTIR) spectroscopy. The microtensile bond strength (µTBS) and nanoleakage were evaluated at 24 h and after 10,000 thermocycles. FIS and ICT + C showed significantly higher µTBS than the control group at 24 h. CPIC, ICT + C, FIS + C, and SIB + C showed significantly higher µTBS than the control group after thermocycling. After thermocycling, silver infiltration into the hybrid layer and interfacial gaps was more noticeable in the control group than in the other groups. The FTIR spectra revealed the formation of apatitic minerals in the demineralized dentin in the flavonoid and CPIC combination groups. The pretreatment of demineralized dentin with flavonoids and CPIC improved dentin bonding stability. The flavonoid and CPIC combinations preserved dentin bond strength.
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