Evidence map›Paper›PMID 35207693›Full record

ReviewJournal of personalized medicine2022

Personalized Dosimetry in Targeted Radiation Therapy: A Look to Methods, Tools and Critical Aspects.

Rachele Danieli, Alessia Milano, Salvatore Gallo, Ivan Veronese, Alessandro Lascialfari, Luca Indovina, Francesca Botta, Mahila Ferrari, Alessandro Cicchetti, Davide Raspanti and 1 more

Abstract readReview
In one paragraph

Review in Journal of personalized medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed.

  1. [Research square · 2026
    Article
  2. Article
  3. Article
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  5. Article
  6. Article
  7. Review
  8. Review
  9. Single-Molecule Biodosimetry.Analytical chemistry · 2025
    Article
  10. Article
  11. Theranostics in nuclear medicine: the era of precision oncology.Medical oncology (Northwood, London, England) · 2025
    Review
  12. Article
  13. Review
  14. Design and Evaluation of a Portable Pinhole SPECT System forDiagnostics (Basel, Switzerland) · 2025
    Article
  15. Review
  16. Review
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Rachele DanieliDipartimento di Fisica, Università degli Studi di Pavia, Via Bassi 6, 27100 Pavia, Italy.ORCID 0000-0001-8013-4938
Alessia MilanoFondazione Policlinico Universitario A. Gemelli IRCCS, Largo F. Vito 1, 00168 Roma, Italy.ORCID 0000-0003-4366-0984
Salvatore GalloDipartimento di Fisica "Aldo Pontremoli", Università degli Studi di Milano, Via Celoria 16, 20133 Milano, Italy.ORCID 0000-0002-5479-4577
Ivan VeroneseDipartimento di Fisica "Aldo Pontremoli", Università degli Studi di Milano, Via Celoria 16, 20133 Milano, Italy.ORCID 0000-0002-3345-4303
Alessandro LascialfariINFN-Pavia Unit, Department of Physics, University of Pavia, Via Bassi 6, 27100 Pavia, Italy.
Luca IndovinaFondazione Policlinico Universitario A. Gemelli IRCCS, Largo F. Vito 1, 00168 Roma, Italy.ORCID 0000-0001-8073-9005
Francesca BottaMedical Physics Unit, European Institute of Oncology IRCCS, Via Giuseppe Ripamonti 435, 20141 Milano, Italy.ORCID 0000-0002-3693-8899
Mahila FerrariMedical Physics Unit, European Institute of Oncology IRCCS, Via Giuseppe Ripamonti 435, 20141 Milano, Italy.
Alessandro CicchettiProstate Cancer Program, Fondazione IRCCS Istituto Nazionale dei Tumori, Via Giacomo Venezian, 1, 20133 Milano, Italy.
Davide RaspantiTemasinergie S.p.A., Via Marcello Malpighi 120, 48018 Faenza, Italy.
Marta CremonesiRadiation Research Unit, European Institute of Oncology IRCCS, Via Giuseppe Ripamonti 435, 20141 Milano, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Targeted radiation therapy (TRT) is a strategy increasingly adopted for the treatment of different types of cancer. The urge for optimization, as stated by the European Council Directive (2013/59/EURATOM), requires the implementation of a personalized dosimetric approach, similar to what already happens in external beam radiation therapy (EBRT). The purpose of this paper is to provide a thorough introduction to the field of personalized dosimetry in TRT, explaining its rationale in the context of optimization and describing the currently available methodologies. After listing the main therapies currently employed, the clinical workflow for the absorbed dose calculation is described, based on works of the most experienced authors in the literature and recent guidelines. Moreover, the widespread software packages for internal dosimetry are presented and critical aspects discussed. Overall, a selection of the most important and recent articles about this topic is provided.

Indexed as

molecular radiation therapypersonalized dosimetryselective intra-arterial radiation therapytargeted radiation therapytreatment planning systems

Identifiers

PMID35207693
PMCPMC8874397

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.