ArticleJournal of personalized medicine2022
Clinical Disease Severity Mediates the Relationship between Stride Length and Speed and the Risk of Falling in Parkinson's Disease.
Article in Journal of personalized medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.
- Markerless Motion Capture to Quantify Functional Performance in Neurodegeneration: Systematic Review.JMIR aging · 2024Pooled it
- The relationships between lower-extremity dexterity and fall risk, fear of falling, and walking skills in People with Parkinson's disease.Irish journal of medical science · 2026Article
- Modified Extended Kalman Filter and Long Short-Term Memory-Based Framework for Reliable Stride-Length Estimation Using Inertial Sensors.Sensors (Basel, Switzerland) · 2026Article
- Walking Speed Explains Apparent Ground Reaction Force Differences in Parkinson's Disease: A Waveform-Level SPM Analysis During Normal and Virtual Reality Walking.Parkinson's disease · 2026Article
- Is gaitrite system sensitive in discriminating gait pattern of subjects affected by Charcot Marie tooth? A pilot study.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025Article
- A longitudinal rat forelimb model for assessing in vivo neuromuscular function following extremity reperfusion injury.Lab animal · 2025Article
- Impact of forward and backward walking on gait parameters across parkinson's disease stages and severity: a prospective observational study.BMC neurology · 2025Observational
- Postural sway serves as a predictive biomarker in balance and gait assessments for diabetic peripheral neuropathy screening: a community-based study.Journal of neuroengineering and rehabilitation · 2025Article
- Mediation analysis for integrating motor symptoms of Parkinson's disease, cognitive function, and gait characteristics.Frontiers in neurology · 2025Article
- Lower-Limb Exoskeletons for Gait Training in Parkinson's Disease: The State of the Art and Future Perspectives.Healthcare (Basel, Switzerland) · 2024Review
- Exploring the role of anticipatory postural adjustment duration within APA2 subphase as a potential mediator between clinical disease severity and fall risk in Parkinson's disease.Frontiers in aging neuroscience · 2024Article
- Investigating spatiotemporal and kinematic gait parameters in individuals with Parkinson's disease with a history of freezing of gait and exploring the effects of dopaminergic therapy on freezing of gait subtypes.Frontiers in neuroscience · 2024Article
- Validation of Gait Measurements on Short-Distance Walkways Using Azure Kinect DK in Patients Receiving Chronic Hemodialysis.Journal of personalized medicine · 2023Article
- Assessing the Feasibility of Using Electrochemical Skin Conductance as a Substitute for the Quantitative Sudomotor Axon Reflex Test in the Composite Autonomic Scoring Scale and Its Correlation with Composite Autonomic Symptom Scale 31 in Parkinson's Disease.Journal of clinical medicine · 2023Article
- The Executive-Function-Related Cognitive-Motor Dual Task Walking Performance and Task Prioritizing Effect on People with Parkinson's Disease.Healthcare (Basel, Switzerland) · 2023Article
- Useful outcome measures in INPH patients evaluation.Frontiers in neurology · 2023Article
Corrections and comments
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Authors and funding
13 authors at 2 institutions in 2 countries.
Funding
Abstract
The shuffling gait with slowed speed and reduced stride length has been considered classic clinical features in idiopathic Parkinson's disease (PD), and the risk of falling increases as the disease progresses. This raises the possibility that clinical disease severity might mediate the relationship between stride length and speed and the risk of falling in patients with PD. Sixty-one patients with PD patients underwent the clinical scores as well as quantitative biomechanical measures during walking cycles before and after dopamine replacement therapy. Mediation analysis tests whether the direct effect of an independent variable (stride length and speed) on a dependent variable (three-step fall prediction model score) can be explained by the indirect influence of the mediating variable (Unified Parkinson's Disease Rating Scale (UPDRS) total scores). The results demonstrate that decreased stride length, straight walking speed, and turning speed is associated with increased three-step fall prediction model score (r = -0.583,
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.