Evidence map›Paper›PMID 35207673›Full record

ArticleJournal of personalized medicine2022

Kidney Function Change and All-Cause Mortality in Denosumab Users with and without Chronic Kidney Disease.

Ping-Hsun Wu, Ming-Yen Lin, Teng-Hui Huang, Tien-Ching Lee, Sung-Yen Lin, Chung-Hwan Chen, Mei-Chuan Kuo, Yi-Wen Chiu, Jer-Ming Chang, Shang-Jyh Hwang

Open access · goldAbstract read
In one paragraph

Article in Journal of personalized medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Ping-Hsun WuDepartment of Internal Medicine, Division of Nephrology, Kaohsiung Medical University Hospital, Kaohsiung 80756, Taiwan.ORCID 0000-0003-1021-8161
Ming-Yen LinDepartment of Internal Medicine, Division of Nephrology, Kaohsiung Medical University Hospital, Kaohsiung 80756, Taiwan.ORCID 0000-0002-8194-4833
Teng-Hui HuangDepartment of Internal Medicine, Division of Nephrology, Kaohsiung Medical University Hospital, Kaohsiung 80756, Taiwan.
Tien-Ching LeeDepartment of Orthopedics, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung 80756, Taiwan.ORCID 0000-0002-1510-8079
Sung-Yen LinDepartment of Orthopedics, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung 80756, Taiwan.ORCID 0000-0002-4191-2183
Chung-Hwan ChenDepartment of Orthopedics, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung 80756, Taiwan.ORCID 0000-0001-8941-4792
Mei-Chuan KuoDepartment of Internal Medicine, Division of Nephrology, Kaohsiung Medical University Hospital, Kaohsiung 80756, Taiwan.ORCID 0000-0003-0244-7685
Yi-Wen ChiuDepartment of Internal Medicine, Division of Nephrology, Kaohsiung Medical University Hospital, Kaohsiung 80756, Taiwan.
Jer-Ming ChangDepartment of Internal Medicine, Division of Nephrology, Kaohsiung Medical University Hospital, Kaohsiung 80756, Taiwan.ORCID 0000-0003-0071-1710
Shang-Jyh HwangDepartment of Internal Medicine, Division of Nephrology, Kaohsiung Medical University Hospital, Kaohsiung 80756, Taiwan.
Kaohsiung Medical University · TW

Funding

Kaohsiung Medical University KMU-DK(B)110003 and KMU-Q108024Kaohsiung Medical University Chung-Ho Memorial Hospital KMUH-DK(B)110003-1, KMUH110-0M13, KMUH110-0M12, KMUH109-9R16, KMUH108-8M11, and KMUH106-6T03Kaohsiung Municipal Ta-Tung Hospital kmtth-109-R006Ministry of Science and Technology MOST 109-2314-B-037-088
6 · The paper itself

Abstract

Denosumab is approved for osteoporosis treatment in subjects with and without chronic kidney disease (CKD). Confirmation is required for its safety, treatment adherence, renal function effect, and mortality in patients with CKD. A retrospective cohort study was conducted to compare new users of denosumab in terms of their two-year drug adherence in all participants (overall cohort) and CKD participants (CKD subcohort), which was defined as baseline estimated glomerular filtration rate (eGFR) less than 60 mL/min/1.73 m

Indexed as

adherencechronic kidney diseasedenosumabmortalityrenal function

Identifiers

PMID35207673
PMCPMC8875658
OpenAlexW4210560045

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.