Evidence map›Paper›PMID 35207601›Full record

ReviewLife (Basel, Switzerland)2022

Postoperative Delirium and Postoperative Cognitive Dysfunction in Patients with Elective Hip or Knee Arthroplasty: A Narrative Review of the Literature.

Petros Kitsis, Theopisti Zisimou, Ioannis Gkiatas, Ioannis Kostas-Agnantis, Ioannis Gelalis, Anastasios Korompilias, Emilios Pakos

Registry-linked trialOpen access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Life (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05537155 (Buccal Acupuncture for Delirium Treatment in Older Patients Recovering From Orthopedic Surgery), which is not on this map. Cited by 34 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 3 pooled it
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05537155 nawithdrawnnot on this map

Buccal Acupuncture for Delirium Treatment in Older Patients Recovering From Orthopedic Surgery: a Randomized Controlled Trial

TypeinterventionalSponsorPeking University First HospitalRan2022 to 2024Enrolled0ConditionsOlder Patients, Orthopedic Surgery, Postoperative Delirium, AcupunctureArmsBuccal acupuncture in addition to routine care, Routine care
3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 3 syntheses or guidelines pooled it, 40 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 2 countries.

Petros KitsisDepartment of Orthopaedic Surgery, School of Medicine, University of Ioannina, Stavrou Niarchou Street, 45500 Ioannina, Greece.ORCID 0000-0001-6110-1436
Theopisti ZisimouDepartment of Orthopaedic Surgery, School of Medicine, University of Ioannina, Stavrou Niarchou Street, 45500 Ioannina, Greece.ORCID 0000-0002-5878-6507
Ioannis GkiatasDepartment of Orthopaedic Surgery, School of Medicine, University of Ioannina, Stavrou Niarchou Street, 45500 Ioannina, Greece.ORCID 0000-0003-2541-5467
Ioannis Kostas-AgnantisDepartment of Orthopaedic Surgery, School of Medicine, University of Ioannina, Stavrou Niarchou Street, 45500 Ioannina, Greece.
Ioannis GelalisDepartment of Orthopaedic Surgery, School of Medicine, University of Ioannina, Stavrou Niarchou Street, 45500 Ioannina, Greece.
Anastasios KorompiliasDepartment of Orthopaedic Surgery, School of Medicine, University of Ioannina, Stavrou Niarchou Street, 45500 Ioannina, Greece.
Emilios PakosDepartment of Orthopaedic Surgery, School of Medicine, University of Ioannina, Stavrou Niarchou Street, 45500 Ioannina, Greece.
University of Ioannina · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Postoperative delirium (POD) and postoperative cognitive dysfunction (POCD) are common complications following total knee arthroplasty (TKA) and total hip arthroplasty (THA), affecting the length of hospital stay and increasing medical complications. Although many papers have been published on both conditions in this setting, no reviews have currently been written. Thus, the purpose of our study is to summarize the current literature and provide information about POD and POCD following elective THA or TKA. Our literature search was conducted in the electronic databases PubMed and the Cochrane library. We found that POD is a common complication following elective THA or TKA, with a median incidence of 14.8%. Major risk factors include older age, cognitive impairment, dementia, preoperative (pre-op) comorbidities, substance abuse, and surgery for fracture. Diagnosis can be achieved using tools such as the confusion assessment method (CAM), which is sensitive, specific, reliable, and easy to use, for the identification of POD. Treatment consists of risk stratification and the implementation of a multiple component prevention protocol. POCD has a median incidence of 19.3% at 1 week, and 10% at 3 months. Risk factors include older age, high BMI, and cognitive impairment. Treatment consists of reversing risk factors and implementing protocols in order to preserve physiological stability. POD and POCD are common and preventable complications following TKA and THA. Risk stratification and specific interventions can lower the incidence of both syndromes. Every physician involved in the care of such patients should be informed on every aspect of these conditions in order to provide the best care for their patients.

Indexed as

cognitive dysfunctiondeliriumelective total hip replacementelective total knee replacementmental disorderneurobehavioral manifestations

Identifiers

PMID35207601
PMCPMC8878498
OpenAlexW4214507161

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.