Evidence map›Paper›PMID 35207557›Full record

ReviewLife (Basel, Switzerland)2022

The Potential Role of Nutrition in Lung Cancer Establishment and Progression.

Chiara Porro, Maria Ester La Torre, Nicola Tartaglia, Tarek Benameur, Mario Santini, Antonio Ambrosi, Giovanni Messina, Giuseppe Cibelli, Alfonso Fiorelli, Rita Polito and 1 more

Open access · goldAbstract readReview
In one paragraph

Review in Life (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 3 pooled it
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 3 syntheses or guidelines pooled it, 19 citations in OpenAlex.

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  14. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Chiara PorroDepartment of Clinical and Experimental Medicine, University of Foggia, 71122 Foggia, Italy.ORCID 0000-0002-7526-6968
Maria Ester La TorreDepartment of Clinical and Experimental Medicine, University of Foggia, 71122 Foggia, Italy.ORCID 0000-0002-6035-7824
Nicola TartagliaDepartment of Medical Additionally, Surgical Sciences, University of Foggia, 71100 Foggia, Italy.ORCID 0000-0001-6845-7080
Tarek BenameurDepartment of Biomedical Sciences, College of Medicine, King Faisal University, Al-Ahsa 31982, Saudi Arabia.
Mario SantiniDepartment of Translational Medicine, Università degli Studi della Campania "Luigi Vanvitelli", 80138 Naples, Italy.ORCID 0000-0003-1162-7805
Antonio AmbrosiDepartment of Medical Additionally, Surgical Sciences, University of Foggia, 71100 Foggia, Italy.
Giovanni MessinaDepartment of Clinical and Experimental Medicine, University of Foggia, 71122 Foggia, Italy.ORCID 0000-0002-0011-867X
Giuseppe CibelliDepartment of Clinical and Experimental Medicine, University of Foggia, 71122 Foggia, Italy.
Alfonso FiorelliDepartment of Translational Medicine, Università degli Studi della Campania "Luigi Vanvitelli", 80138 Naples, Italy.ORCID 0000-0002-0628-613X
Rita PolitoDepartment of Clinical and Experimental Medicine, University of Foggia, 71122 Foggia, Italy.
Gaetana MessinaDepartment of Translational Medicine, Università degli Studi della Campania "Luigi Vanvitelli", 80138 Naples, Italy.
University of Foggia · ITUniversity of Campania "Luigi Vanvitelli" · ITKing Faisal University · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lung cancer is a devastating disease with a high incidence and low survival rates, so recent studies have focused on analyzing the risk factors that might prevent this disease from developing or have protective/therapeutic effects. Nutrition is an important key factor in the prevention and treatment of lung cancer. Various factors appear to be involved in the development of the latter, such as cigarette smoking or certain external environmental factors. The increase in oxidative stress is therefore an integral part of the carcinogenesis process. The biological role of bioactive factors derived from adipose tissue, mainly adipokines, is implicated in various cancers, and an increasing body of evidence has shown that certain adipocytokines contribute to the development, progression and prognosis of lung cancer. Not all adipokines stimulate tumor growth; in fact, adiponectin inhibits carcinogenesis by regulating both cell growth and the levels of inflammatory cytokines. Adiponectin expression is deregulated in several cancer types. Many nutritional factors have been shown to increase adiponectin levels and therefore could be used as a new therapeutic strategy for combating lung cancer. In addition, foods with antioxidant and anti-inflammatory properties play a key role in the prevention of many human diseases, including lung cancer. The purpose of this review is to analyze the role of diet in lung cancer in order to recommend dietary habit and lifestyle changes to prevent or treat this pathology.

Indexed as

correct nutritionhealthy lifestyleinflammationlung cancerobesityoxidative stress

Identifiers

PMID35207557
PMCPMC8877211
OpenAlexW4212830026

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.