Evidence map›Paper›PMID 35207524›Full record

ArticleLife (Basel, Switzerland)2022

Maggot Extract Interrupts Bacterial Biofilm Formation and Maturation in Combination with Antibiotics by Reducing the Expression of Virulence Genes.

Mustafa Becerikli, Christoph Wallner, Mehran Dadras, Johannes M Wagner, Stephanie Dittfeld, Birger Jettkant, Falk Gestmann, Heinz Mehlhorn, Tim Mehlhorn-Diehl, Marcus Lehnhardt and 1 more

Abstract read
In one paragraph

Article in Life (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
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  3. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Mustafa BecerikliDepartment of Plastic and Reconstructive Surgery, BG University Hospital Bergmannsheil, Ruhr-University Bochum, 44789 Bochum, Germany.ORCID 0000-0002-2695-5273
Christoph WallnerDepartment of Plastic and Reconstructive Surgery, BG University Hospital Bergmannsheil, Ruhr-University Bochum, 44789 Bochum, Germany.
Mehran DadrasDepartment of Plastic and Reconstructive Surgery, BG University Hospital Bergmannsheil, Ruhr-University Bochum, 44789 Bochum, Germany.ORCID 0000-0003-1283-2982
Johannes M WagnerDepartment of Plastic and Reconstructive Surgery, BG University Hospital Bergmannsheil, Ruhr-University Bochum, 44789 Bochum, Germany.
Stephanie DittfeldDepartment of Plastic and Reconstructive Surgery, BG University Hospital Bergmannsheil, Ruhr-University Bochum, 44789 Bochum, Germany.
Birger JettkantDepartment of General and Trauma Surgery, BG University Hospital Bergmannsheil, Ruhr-University Bochum, 44789 Bochum, Germany.
Falk GestmannAlpha-Biocare GmbH, 41468 Neuss, Germany.ORCID 0000-0002-1559-8397
Heinz MehlhornAlpha-Biocare GmbH, 41468 Neuss, Germany.
Tim Mehlhorn-DiehlAlpha-Biocare GmbH, 41468 Neuss, Germany.
Marcus LehnhardtDepartment of Plastic and Reconstructive Surgery, BG University Hospital Bergmannsheil, Ruhr-University Bochum, 44789 Bochum, Germany.
Björn BehrDepartment of Plastic and Reconstructive Surgery, BG University Hospital Bergmannsheil, Ruhr-University Bochum, 44789 Bochum, Germany.

Funding

Federal Ministry for Economic Affairs and Energy ZF4048804NK7
6 · The paper itself

Abstract

Biofilms are aggregates of bacteria encased in an extracellular polymer matrix that acts as a diffusion barrier protecting the microbial community. Bacterial communication occurs by small signaling molecules called quorum sensing (QS) factors, which are involved in the activation of virulence genes and formation of biofilms. Larvae of the green bottle blowfly

Indexed as

antibiotic resistancebiofilmLucilia sericatamaggot extractPseudomonas aeruginosaStaphylococcus aureusvirulence genes

Identifiers

PMID35207524
PMCPMC8875949

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.