Evidence map›Paper›PMID 35207487›Full record

ArticleLife (Basel, Switzerland)2022

Microangiopathy in Inflammatory Diseases-Strategies in Surgery of the Lower Extremity.

Christoph Biehl, Lotta Biehl, Ingo Helmut Tarner, Ulf Müller-Ladner, Christian Heiss, Martin Heinrich

Open access · goldAbstract read
In one paragraph

Article in Life (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 57% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Microangiopathy in Rheumatic Diseases.Life (Basel, Switzerland) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Christoph BiehlDepartment of Trauma, Hand and Reconstructive Surgery, University Hospital Giessen, 35392 Giessen, Germany.ORCID 0000-0003-2981-5062
Lotta BiehlMedical Faculty Heidelberg, Heidelberg University, 69117 Heidelberg, Germany.
Ingo Helmut TarnerDepartment of Rheumatology and Clinical Immunology, Campus Kerckhoff, Justus-Liebig-University of Giessen, Benekestr., 61231 Bad Nauheim, Germany.
Ulf Müller-LadnerDepartment of Rheumatology and Clinical Immunology, Campus Kerckhoff, Justus-Liebig-University of Giessen, Benekestr., 61231 Bad Nauheim, Germany.
Christian HeissDepartment of Trauma, Hand and Reconstructive Surgery, University Hospital Giessen, 35392 Giessen, Germany.
Martin HeinrichDepartment of Trauma, Hand and Reconstructive Surgery, University Hospital Giessen, 35392 Giessen, Germany.ORCID 0000-0003-0858-1551
Universitätsklinikum Gießen und Marburg · DEJustus-Liebig-Universität Gießen · DEHeidelberg University · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPatients with an inflammatory disease frequently develop chronic angiopathy of the capillaries. Due to this pathology, there is an increased rate of complications in lower extremity surgical procedures. It is not uncommon for microangiopathic wound healing disorders to cause deep infections and fistulas, which lead to prolonged courses and hospitalizations. In addition, adhesions and ossifications of the contractile elements occur regularly. This sometimes results in serious limitations of the mobility of the patients. The study aims to present the results of a combination of vacuum and physical therapy. PATIENT AND

methodsA retrospective study of six patients with systemic sclerosis undergoing joint-related procedures of the lower extremity between 2015 and 2020 was performed. In addition to characterization of the patients and therapy, special attention was paid to cutaneous wound healing, affection of the fascia and displacement layers, and sclerosis of the muscle and tendon insertion.

resultsThe characterized structures (skin, tendon, fascia) show pathological changes at the microangiopathic level, which are associated with delayed healing and less physical capacity. Early suture removal regularly results in secondary scar dehiscence. With a stage-adapted vacuum therapy with sanitation of the deep structures and later on a dermal vacuum system, healing with simultaneous mobilization of the patients could be achieved in our patient cohort.

conclusionIn the case of necessary interventions on the lower extremity, such as trauma surgery, additional decongestive measures in the sense of regular and sustained lymphatic therapy and adapted physiotherapy are indispensable.

Indexed as

lower extremitysurgical treatmentsystemic sclerosisvacuum therapy

Identifiers

PMID35207487
PMCPMC8876644
OpenAlexW4210338866

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.