Evidence map›Paper›PMID 35207447›Full record

ArticleLife (Basel, Switzerland)2022

Neutrophils in Extravascular Body Fluids: Cytological-Energy Analysis Enables Rapid, Reliable and Inexpensive Detection of Purulent Inflammation and Tissue Damage.

Petr Kelbich, Petr Vachata, Vilem Maly, Tomas Novotny, Jan Spicka, Inka Matuchova, Tomas Radovnicky, Ivan Stanek, Jan Kubalik, Ondrej Karpjuk and 3 more

Open access · goldAbstract read
In one paragraph

Article in Life (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Petr KelbichDepartment of Biomedicine and Laboratory Diagnostics, Faculty of Health Studies, Jan Evangelista Purkinje University and Masaryk Hospital, 401 13 Usti nad Labem, Czech Republic.ORCID 0000-0002-9261-6827
Petr VachataDepartment of Neurosurgery, Faculty of Health Studies, Jan Evangelista Purkinje University and Masaryk Hospital, 401 13 Usti nad Labem, Czech Republic.
Vilem MalyDepartment of Thoracic Surgery, Masaryk Hospital, 401 13 Usti nad Labem, Czech Republic.
Tomas NovotnyDepartment of Orthopaedics, Faculty of Health Studies, Jan Evangelista Purkinje University and Masaryk Hospital, 401 13 Usti nad Labem, Czech Republic.ORCID 0000-0002-3855-0038
Jan SpickaDepartment of Biomedicine and Laboratory Diagnostics, Faculty of Health Studies, Jan Evangelista Purkinje University and Masaryk Hospital, 401 13 Usti nad Labem, Czech Republic.
Inka MatuchovaDepartment of Clinical Immunology and Allergology, Faculty of Medicine and University Hospital, Charles University in Prague, 500 03 Hradec Kralove, Czech Republic.
Tomas RadovnickyDepartment of Neurosurgery, Faculty of Health Studies, Jan Evangelista Purkinje University and Masaryk Hospital, 401 13 Usti nad Labem, Czech Republic.ORCID 0000-0003-3642-0448
Ivan StanekDepartment of Thoracic Surgery, Masaryk Hospital, 401 13 Usti nad Labem, Czech Republic.
Jan KubalikDepartment of Clinical Immunology and Allergology, Faculty of Medicine and University Hospital, Charles University in Prague, 500 03 Hradec Kralove, Czech Republic.
Ondrej KarpjukDepartment of Thoracic Surgery, Masaryk Hospital, 401 13 Usti nad Labem, Czech Republic.
Frantisek SmiskoDepartment of Orthopaedics, Regional Hospital, 360 01 Karlovy Vary, Czech Republic.
Eva HanuljakovaDepartment of Biomedicine and Laboratory Diagnostics, Faculty of Health Studies, Jan Evangelista Purkinje University and Masaryk Hospital, 401 13 Usti nad Labem, Czech Republic.
Jan KrejsekDepartment of Clinical Immunology and Allergology, Faculty of Medicine and University Hospital, Charles University in Prague, 500 03 Hradec Kralove, Czech Republic.
Charles University · CZMasaryk University · CZMuzeum Karlovy Vary · CZ

Funding

Charles University in Prague, Faculty of Medicine in Hradec Králové, Czech Republic PROGRES Q40/10Krajská Zdravotní IGA-KZ-2021-1-2
6 · The paper itself

Abstract

The simultaneous cytological and metabolic investigation of various extravascular body fluids (EBFs) provides clinically relevant information about the type and intensity of the immune response in particular organ systems. The oxidative burst of professional phagocytes with the concomitant production of reactive oxygen species consumes a large amount of oxygen and is the cause of switch to the development of anaerobic metabolism. We assessed the relationships between percentages of neutrophils, aerobic and anaerobic metabolism, and tissue damage via the determination of aspartate aminotransferase catalytic activities (AST) in cerebrospinal fluid (CSF), pleural effusions (PE), abdominal effusions (AE), and synovial fluids (SF).

Indexed as

abdominal effusionaspartate aminotransferasecerebrospinal fluidcoefficient of energy balanceneutrophilspleural effusionpurulent inflammationsynovial fluid

Identifiers

PMID35207447
PMCPMC8877237
OpenAlexW4206542641

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.