Evidence map›Paper›PMID 35207282›Full record

ArticleJournal of clinical medicine2022

Antibodies to

Charlotte de Vries, Guillermo Ruacho, Elin Kindstedt, Barbara Aleksandra Potempa, Jan Potempa, Björn Klinge, Pernilla Lundberg, Elisabet Svenungsson, Karin Lundberg

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

  1. Association ofJournal of clinical medicine · 2026
    Review
  2. Review
  3. Review
  4. Article
  5. Article
  6. RMD open · 2025
    Article
  7. CRISPRJournal of oral microbiology · 2025
    Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 3 countries.

Charlotte de VriesDivision of Rheumatology, Department of Medicine Solna, Karolinska Institutet and Center for Molecular Medicine, Karolinska University Hospital, 171 76 Stockholm, Sweden.ORCID 0000-0003-4513-4128
Guillermo RuachoDivision of Rheumatology, Department of Medicine Solna, Karolinska Institutet and Center for Molecular Medicine, Karolinska University Hospital, 171 76 Stockholm, Sweden.
Elin KindstedtDivision of Rheumatology, Department of Medicine Solna, Karolinska Institutet and Center for Molecular Medicine, Karolinska University Hospital, 171 76 Stockholm, Sweden.ORCID 0000-0003-2448-4049
Barbara Aleksandra PotempaDepartment of Oral Immunology & Infectious Diseases, University of Louisville, Louisville, KY 40202, USA.
Jan PotempaDepartment of Oral Immunology & Infectious Diseases, University of Louisville, Louisville, KY 40202, USA.
Björn KlingeDivision of Oral Diseases, Department of Dental Medicine, Karolinska Institutet, 171 77 Stockholm, Sweden.
Pernilla LundbergSection for Molecular Periodontology, Department of Odontology, Umeå University, 901 85 Umeå, Sweden.
Elisabet SvenungssonDivision of Rheumatology, Department of Medicine Solna, Karolinska Institutet and Center for Molecular Medicine, Karolinska University Hospital, 171 76 Stockholm, Sweden.
Karin LundbergDivision of Rheumatology, Department of Medicine Solna, Karolinska Institutet and Center for Molecular Medicine, Karolinska University Hospital, 171 76 Stockholm, Sweden.ORCID 0000-0001-7625-964X
Karolinska University Hospital · SEJagiellonian University · PLMalmö University · SEUmeå University · SE

Funding

Blocking of IL-6 function to prevent Pg mediated Th17 responseR21DE023207 · NIDCR · UNIVERSITY OF LOUISVILLE · PI POTEMPA, JAN S · 2013 to 2014
$413k
King Gustav V:s 80-year foundation FAI-2016-0273National Science Center 2018/30/A/NZ5/00650NIDCR NIH HHS DE 023207Professor Nanna Svartz's foundation not availableSwedish Research Council 2017-01696Swedish Rheumatism Association R-940746Västerbotten County VLL-645361
6 · The paper itself

Abstract

There is accumulating data suggesting that periodontitis is associated with increased risk of systemic and autoimmune diseases, including cardiovascular disease, rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE), and there is an unmet need to identify these individuals early. With the periodontal bacteria

Indexed as

anti-citrullinated protein antibodiesanti-double stranded DNA antibodiesarginine gingipainsautoimmunitymyocardial infarctionPorphyromonas gingivalisrheumatoid arthritissystemic lupus erythematosus

Identifiers

PMID35207282
PMCPMC8875626
OpenAlexW4213049536

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.