Evidence map›Paper›PMID 35207271›Full record

ReviewJournal of clinical medicine2022

Selective Forms of Therapy in the Treatment of Inflammatory Bowel Diseases.

Anna Kofla-Dłubacz, Katarzyna Akutko, Elżbieta Krzesiek, Tatiana Jamer, Joanna Braksator, Paula Grębska, Tomasz Pytrus, Andrzej Stawarski

Abstract readReview
In one paragraph

Review in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Etiology of IBD-Is It Still a Mystery?International journal of molecular sciences · 2022
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Anna Kofla-Dłubacz2nd Department of Paediatrics, Gastroenterology and Nutrition, Faculty of Medicine, Wroclaw Medical University, M. Sklodowskiej-Curie Str. 50/52, 50-367 Wroclawl, Poland.
Katarzyna Akutko2nd Department of Paediatrics, Gastroenterology and Nutrition, Faculty of Medicine, Wroclaw Medical University, M. Sklodowskiej-Curie Str. 50/52, 50-367 Wroclawl, Poland.
Elżbieta Krzesiek2nd Department of Paediatrics, Gastroenterology and Nutrition, Faculty of Medicine, Wroclaw Medical University, M. Sklodowskiej-Curie Str. 50/52, 50-367 Wroclawl, Poland.
Tatiana Jamer2nd Department of Paediatrics, Gastroenterology and Nutrition, Faculty of Medicine, Wroclaw Medical University, M. Sklodowskiej-Curie Str. 50/52, 50-367 Wroclawl, Poland.
Joanna Braksator2nd Department of Paediatrics, Gastroenterology and Nutrition, Faculty of Medicine, Wroclaw Medical University, M. Sklodowskiej-Curie Str. 50/52, 50-367 Wroclawl, Poland.ORCID 0000-0003-0071-2959
Paula Grębska2nd Department of Paediatrics, Gastroenterology and Nutrition, Faculty of Medicine, Wroclaw Medical University, M. Sklodowskiej-Curie Str. 50/52, 50-367 Wroclawl, Poland.
Tomasz Pytrus2nd Department of Paediatrics, Gastroenterology and Nutrition, Faculty of Medicine, Wroclaw Medical University, M. Sklodowskiej-Curie Str. 50/52, 50-367 Wroclawl, Poland.
Andrzej Stawarski2nd Department of Paediatrics, Gastroenterology and Nutrition, Faculty of Medicine, Wroclaw Medical University, M. Sklodowskiej-Curie Str. 50/52, 50-367 Wroclawl, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Selective interference with the functioning of the immune system consisting of the selective blockade of pro-inflammatory factors is a modern, promising, and developing strategy for the treatment of diseases resulting from dysregulation of the immune system, including inflammatory bowel disease. Inhibition of the TNF alpha pathway, group 12/23 cytokines, and lymphocyte migration is used in the treatment of severe or moderate ulcerative colitis and Crohn's disease. Intracellular signal transduction by influencing the phosphorylation of SAT (signal transducer and activator of transcription) proteins remains in clinical trials.

Indexed as

IBDlymphocyte migrationpro-inflammatory cytokinestreatment

Identifiers

PMID35207271
PMCPMC8879972

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.