ArticleMembranes2022
Permeate Flux in Ultrafiltration Processes-Understandings and Misunderstandings.
Article in Membranes, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- The current landscape of mRNA therapy and the strategies for mRNA purification and dsRNA removal.Journal of biomedical science · 2026Review
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- Digital Twin for the Production of hMSC-Derived Extracellular Vesicles for Applications in Cell and Gene Therapy toward Autonomous Operation.ACS omega · 2025Article
- Purifying circular RNA by ultrafiltration.Separation and purification technology · 2025Article
- A Model-Driven Approach to Assessing the Fouling Mechanism in the Crossflow Filtration of Laccase Extract fromMembranes · 2025Article
- Scalable Membrane Enabled One-Pot Liquid-Phase Oligonucleotide Synthesis.Organic process research & development · 2025Article
- Ultrafiltration of Whole Milk: Impact of Homogenization and Ultrafiltration Temperature on Processing Efficiency and Component Retention.Foods (Basel, Switzerland) · 2025Article
- Article
- Assessing the Manufacturability and Critical Quality Attribute Profiles of Anti-IL-8 Immunoglobulin G Mutant Variants.Molecular pharmaceutics · 2024Article
- A Carrier Phase Ultrafiltration and Backflow Recovery Technique for Purification of Biological Macromolecules.Membranes · 2024Article
- Digital Twin for Continuous Production of Virus-like Particles toward Autonomous Operation.ACS omega · 2024Article
- Article
- Efficiency of Fabricated Adsorptive Polysulfone Mixed Matrix Membrane for Acetic Acid Separation.Membranes · 2023Article
- Membrane-Based Solvent Exchange Process for Purification of API Crystal Suspensions.Membranes · 2023Article
- A Hydrodynamic Approach to the Study of HIV Virus-Like Particle (VLP) Tangential Flow Filtration.Membranes · 2022Article
- Application of Cyclized Polyacrylonitrile for Ultrafiltration Membrane Fouling Mitigation.Membranes · 2022Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Concentration polarization refers to the rapid emergence of concentration gradients at a membrane/solution interface resulting from selective transfer through the membrane. It is distinguishable from fouling in at least two ways: (1) the state of the molecules involved (in solution for concentration polarization, although no longer in solution for fouling); and (2) by the timescale, normally less than a minute for concentration polarization, although generally at least two or more orders of magnitude more for fouling. Thus the phenomenon of flux decline occurring over a timescale of tens of minutes should not be attributed to concentration polarization establishing itself. This distinction and a number of questions surrounding modelling are addressed and clarified. There are two paradigmatic approaches for modelling flux, one uses the overall driving force (in which case allowance for osmotic effects are expressed as additional resistances) and the other uses the net driving force across the separating layer or fouled separating layer, although often the two are unfortunately comingled. In the discussion of flux decline models' robust approaches for the determination of flux-time relationships, including the integral method of fouling analysis, are discussed and various concepts clarified. The final section emphases that for design purposes, pilot plant data are vital.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.