Evidence map›Paper›PMID 35207106›Full record

ReviewMembranes2022

Scramblases as Regulators of Proteolytic

Karina Reiss, Sinje Leitzke, Jana Seidel, Maria Sperrhacke, Sucharit Bhakdi

Open access · goldAbstract readReview
In one paragraph

Review in Membranes, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. Lipid-Facilitated Opening of the ADAM10 Sheddase Revealed by Enhanced Sampling Simulations.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. A Bioengineering Strategy to Control ADAM10 Activity in Living Cells.International journal of molecular sciences · 2023
    Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Karina ReissDepartment of Dermatology, University of Kiel, 24105 Kiel, Germany.ORCID 0000-0001-5140-2235
Sinje LeitzkeDepartment of Dermatology, University of Kiel, 24105 Kiel, Germany.
Jana SeidelDepartment of Dermatology, University of Kiel, 24105 Kiel, Germany.
Maria SperrhackeDepartment of Dermatology, University of Kiel, 24105 Kiel, Germany.
Sucharit BhakdiIndependent Researcher, 24105 Kiel, Germany.
Christian-Albrechts-Universität zu Kiel · DEClinical Research Center Kiel · DE

Funding

Deutsche Forschungsgemeinschaft 125440785 (SFB877; A4)
6 · The paper itself

Abstract

Proteolytic ectodomain release is a key mechanism for regulating the function of many cell surface proteins. The sheddases

Indexed as

activationADAM10ADAM17cell membrane asymmetryphosphatidylserinescramblases

Identifiers

PMID35207106
PMCPMC8880048
OpenAlexW4210438627

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.