Evidence map›Paper›PMID 35207030›Full record

ArticleMembranes2022

Salvatore G De-Simone, Paloma Napoleão-Pêgo, Priscila S Gonçalves, Guilherme C Lechuga, Arnaldo Mandonado, Carlos Graeff-Teixeira, David W Provance

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Membranes, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Salvatore G De-SimoneCenter of Technological Development in Health (CDTS), National Institute of Science and Technology for Innovation on Neglected Diseases (INCT-IDN), FIOCRUZ, Rio de Janeiro 21040-900, RJ, Brazil.ORCID 0000-0002-2172-656X
Paloma Napoleão-PêgoCenter of Technological Development in Health (CDTS), National Institute of Science and Technology for Innovation on Neglected Diseases (INCT-IDN), FIOCRUZ, Rio de Janeiro 21040-900, RJ, Brazil.
Priscila S GonçalvesCenter of Technological Development in Health (CDTS), National Institute of Science and Technology for Innovation on Neglected Diseases (INCT-IDN), FIOCRUZ, Rio de Janeiro 21040-900, RJ, Brazil.
Guilherme C LechugaCenter of Technological Development in Health (CDTS), National Institute of Science and Technology for Innovation on Neglected Diseases (INCT-IDN), FIOCRUZ, Rio de Janeiro 21040-900, RJ, Brazil.ORCID 0000-0003-4538-3802
Arnaldo MandonadoLaboratory of Biology and Parasitology of Wild Mammals Reservoirs, Oswaldo Cruz Institute, FIOCRUZ, Rio de Janeiro 21040-360, RJ, Brazil.
Carlos Graeff-TeixeiraInfectious Diseases Unit, Department of Pathology, Federal University of Espirito Santo, Vitória 29075-910, ES, Brazil.
David W ProvanceCenter of Technological Development in Health (CDTS), National Institute of Science and Technology for Innovation on Neglected Diseases (INCT-IDN), FIOCRUZ, Rio de Janeiro 21040-900, RJ, Brazil.ORCID 0000-0002-9824-0672
Fundação Oswaldo Cruz · BRUniversidade Federal Fluminense · BRUniversidade Federal do Espírito Santo · BR

Funding

National Council for Scientific and Technological Development #470701-2014-5
6 · The paper itself

Abstract

backgroundAngiostrongyliasis, the leading cause universal of eosinophilic meningitis, is an emergent disease due to MATERIAL AND

methodsUsing bioinformatics tools, the putative presenilin (PS) protein C7BVX5-1 was characterized structurally and phylogenetically. A peptide microarray approach was employed to identify single and specific epitopes, and tetrameric epitope peptides were synthesized to evaluate their performance in an ELISA-peptide assay.

resultsThe data showed that the

conclusionsOur data show that the putative AgPS is an atypical multi-pass transmembrane protein and indicate that the protein is an excellent immunological target with two (PsAg3 and PsAg9)

Indexed as

Angiostrongylus cantonensisaspartyl proteaseB epitopescharacterizationELISAimmunological diagnosispresenilin-liketransmembrane protease

Identifiers

PMID35207030
PMCPMC8878667
OpenAlexW4206374970

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.